Results 91 to 100 of about 327,872 (261)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Study the Effect of Soil Compaction and Biochar on Some Soil Physical Parameters

open access: yesمجلة ديالى للعلوم الزراعية
An experiment was conducted to evaluate the effect of soil compaction levels and biochar addition on some soil physical parameters, namely; bulk density, particle density, soil porosity, hydraulic conductivity and infiltration.
Ali Kadhim Ahmed   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

SOIL RESPIRATION AND BULK DENSITY UNDER ORGANIC AND CONVENTIONAL FARMING SYSTEMS

open access: yesColloquium Agrariae, 2019
The aim of this study was to evaluate, in the field, the soil respiration and bulk density under conventional and organic farming plots. The evaluations were made in different plots established as conventional farming system and organic farming system ...
Antonio Silva   +5 more
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Analytical modelling of soil porosity and bulk density across the soil organic matter and land-use continuum. [PDF]

open access: yesSci Rep, 2022
Robinson DA   +9 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Study on the Correlation Between Mechanical Properties, Water Absorption, and Bulk Density of PVA Fiber-Reinforced Cement Matrix Composites

open access: yesBuildings
Fiber-reinforced cement matrix composites (CMCs) have gained significant attention due to their ability to enhance material properties for use in demanding environments.
Wen Xu   +9 more
doaj   +1 more source

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