Results 151 to 160 of about 409,720 (306)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

The effects of tyre systems on the depth and severity of compaction [PDF]

open access: yes, 2006
High value crops such as peas for the frozen vegetable market have to be harvested at the optimum point for quality, regardless of field conditions. Six wheeled pea harvesters with a gross weight of 27 t, giving a wheel load of 4.5 t are required to move
Stranks, Simon Nicholas
core  

Bulk density and angle of repose of coal

open access: yes, 2007
This thesis reports a study on the effects of size distribution, moisture content and oil addition on bulk density and angle of repose of coal. The experimental work includes four stages.
Liu, Chang
core   +1 more source

BULK DENSITY AND COMPACT BULK DENSITY OF RICE BRAN FROM VARIOUS REGENCIES MIXED WITH RICE HUSK

open access: yesMajalah Ilmiah Peternakan
Rice bran mixed with rice husk often occurs in the feed industry, as a result of scarcity of rice bran as animal feed. The aim of the study was to study the heap density and compaction density of rice bran obtained from various districts mixed with rice husk.
ALFARESI A. Y.   +2 more
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Compactación de un suelo argiudol típico por tráfico en un sistema de producción de forrajes

open access: yesCiencia del Suelo
Entre los diversos procesos que conducen al deterioro de la estructura del suelo, la compactación inducida por tráfico vehicular pareciera ser uno de los desafíos más importante, para una agricultura sustentable. Para un suelo dado, la distribución de la
Matilde Mur, Roberto Hernán Balbuena
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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