Results 111 to 120 of about 2,023,562 (328)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

BİTİRME VE CİLA İŞLEMİNİN BİR BULK FİLL KOMPOZİT REZİNİN RENK STABİLİTESİNE ETKİSİ

European Annals of Dental Sciences, 2017
Bu çalışmanın amacı uygulanan bitirme ve cila işleminin bir bulk fill kompozit rezinin renk stabilitesine etkisinin değerlendirilmesidir. 2 mm kalınlığında ve 8 mm çapında pleksiglass kalıplar kullanılarak 50 adet Bulk fill kompozit rezin örneği X-tra ...
İlahe Mutafayeva, Osman Gökay
doaj  

Bulk-Fill Composites: A Review of the Current Literature.

The journal of adhesive dentistry, 2017
The aim of this article was to provide an overview of the literature on the currently available bulk-fill composites, and to describe the common trends as well as the wide variations. The findings may help the clinician to select the proper material with regard to its applicability in various clinical situations.
Van Ende, Annelies, De Munck, Jan, Lise, Diogo Pedrollo, Van Meerbeek, Bart, Ermis, Banu   +4 more
openaire   +2 more sources

Color stability of Bulk-Fill composite restorations

Journal of Clinical and Experimental Dentistry, 2020
The color stability of the composite resin is an important property that influences its clinical longevity, which remains an inherent challenge to the material. Thus, the purpose of this study was to evaluate the color stability of bulk-fill resins when exposed to dye.Cavities were prepared in 80 bovine incisors, which were randomly assigned into 4 ...
Silva, Marianna-Falcão, Dias, Marlon-Ferreira, Lins-Filho, Paulo-Cardoso, Silva, Claudio-Heliomar-Vicente, Guimarães, Renata-Pedrosa   +4 more
openaire   +5 more sources

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source

Physical and photoelastic properties of bulk-fill and conventional composites

, 2018
Renata Pereira,1 Maria Cecília Caldas Giorgi,2 Rodrigo Barros Esteves Lins,1 Jéssica Dias Theobaldo,1 Débora Alves Nunes Leite Lima,1 Giselle Maria Marchi,1 Flávio Henrique Baggio Aguiar1 1Department of Restorative Dentistry ...
Pereira R, Lins RBE, Lima DANL, Giorgi MCC, Theobaldo JD, Marchi GM, Aguiar FHB   +6 more
core  

Resinas Compostas Bulk Fill: Contração de Polimerização [PDF]

, 2020
As resinas bulk fill (BF) são um grupo de resinas, introduzido recentemente na medicina dentária, que apresentam algumas características peculiares em relação às resinas compostas convencionais.
Padoan, Giorgio
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Evaluation of diferents bulk fill resins: in vitro study

, 2020
Bulk fill dental composites were developed as an alternative to simplify the restorative technique. The simplification of this technique was only possible due to the improvement in the properties of resin-based composites.
Rebello, Heverson Luiz da Costa
core   +1 more source