Results 91 to 100 of about 1,098,643 (378)

His Bundle Electrogram in Bundle-Branch Block [PDF]

Circulation, 1972
Because a great majority of patients with chronic complete heart block have bilateral bundle-branch lesions, it becomes important to recognize earlier degrees of bilateral bundle-branch block. The H-V interval in the His bundle electrogram during unilateral bundle-branch block reflects the conduction primarily through the contralateral bundle branch ...
N, Ranganathan, R, Dhurandhar, J H, Phillips, E D, Wigle   +3 more
openaire   +2 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Impacts of structural properties of myosin II filaments on force generation

eLife
Cells need intracellular forces for their physiological functions, such as migration, cytokinesis, and morphogenesis. The actin cytoskeleton generates a large fraction of the forces via interactions between cytoskeletal components, such as actin filament
Shihang Ding, Pei-En Chou, Shinji Deguchi, Taeyoon Kim   +3 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

An IP Multimedia Subsystem Services Proxy Gateway Based on a JAVA Dynamic Module System

Applied Sciences, 2018
By virtue of the rapid development of the Information and Communication Technology (ICT), people have owned various devices connected to the Internet to enjoy various emerging application services, such as multimedia related services.
Yi-Chun Chang, Jian-Wei Li, Jing-Hong Lv
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Organizational Characteristics Associated With ICU Liberation (ABCDEF) Bundle Implementation by Adult ICUs in Michigan

Critical Care Explorations, 2020
Objectives:. The ICU Liberation (ABCDEF) Bundle can help to improve care and outcomes for ICU patients, but bundle implementation is far from universal.
Juliana Barr, MD, FCCM, Amir A. Ghaferi, MD, MS, FACS, FASMBS, Deena Kelly Costa, PhD, RN, Haley K. Hedlin, PhD, Victoria Y. Ding, MS, Corine Ross, , MHA, Brenda T. Pun, DNP, RN, Sam R. Watson, MSA, MT(ASCP), CPPS, Steven M. Asch, MD, MPH   +8 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Application of generalized differential quadrature method to nonlinear bending analysis of a single SWCNT over a bundle of nanotubes

Archives of Mechanics, 2012
The deformation of an individual single walled carbon nanotube (SWCNT) over a bundle of nanotubes has been studied using the generalized differential quadrature (GDQ) method.
A. Fereidoon, A.M. Babaee, Y. Rostamiyan
doaj   +1 more source