Results 121 to 130 of about 817,701 (334)
Is Bundling Anticompetitive? [PDF]
, 2002 I analyze the implications of bundling on price competition in a market for complementary products. Using a model of imperfect competition with product differentiation, I identify the incentives to bundle for two types of demand functions and study how they change with the size of the bundle. With an inelastic demand, bundling creates an advantage over
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Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
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The holonomy covering space in principal fibre bundles [PDF]
, 1958 Takuya Saeki
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Bundles, linear bundles and principal bundles in the category of differential spaces
Demonstratio Mathematica, 1993 Following the definitions and concepts about the category of differential spaces of the papers of \textit{R. Sikorski} [Colloq. Math. 18, 251-272 (1967; Zbl 0162.251) and Colloq. Math. 24, 45-79 (1971; Zbl 0226.53004)] and \textit{A. Kowalczyk} [Demonstr. Math.
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Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
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Heat Transfer Modeling of Staggered Bundle with Round Tubes Screened by Mesh [PDF]
Problems of the Regional Energetics, 2016 The article presents the results of CFD modeling of heat transfer and aerodynamic drag for the first three rows of cross-flowed staggered bundle consisting of round tubes screened by wire mesh. Geometric model of this bundle was developed.
Dymo B.V. +3 more
doaj
On the differential geometry of tangent bundles of Riemannian manifolds [PDF]
, 1958 Shigeo Sasaki
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Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
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