Results 51 to 60 of about 116,432 (313)

Chest pain and exercise induced left bundle branch block – A clinical dilemma

Journal of Family Medicine and Primary Care, 2019
Exercise-induced left bundle branch block is a rare electrocardiographic phenomenon. We present two patients with angina pectoris who developed left bundle branch block on ECG during treadmill test. The first patient had non-obstructive coronary arteries
Surender Deora, Jai Bharat Sharma, Rahul Choudhary, Atul Kaushik   +3 more
doaj   +1 more source

Current Opinions on New-Onset Left Bundle Branch Block after Transcatheter Aortic Valve Replacement and the Search for Physiological Pacing

Reviews in Cardiovascular Medicine, 2022
Transcatheter aortic valve replacement possesses a high validity for patients with aortic stenosis who are considered high risk for aortic valve replacement surgery, nowadays it is also considered for patients with intermediate risk or even lower risk in
Jiefang Zhang, Yiwen Pan, Bei Wang, Guosheng Fu   +3 more
doaj   +1 more source

Defining Left Bundle Branch Block Patterns in Cardiac Resynchronisation Therapy: A Return to His Bundle Recordings

Arrhythmia & Electrophysiology Review, 2019
Left bundle branch block (LBBB) is associated with improved outcome after cardiac resynchronisation therapy (CRT). One historical presumption of LBBB has been that the underlying pathophysiology involved diffuse disease throughout the distal conduction ...
R. Tung, G. Upadhyay
semanticscholar   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Analysis of electrocardiographic signs in hypertrophic cardiomyopathy before and after septal myectomy. New criterion for proximal left bundle branch block

Российский кардиологический журнал, 2022
Aim. To analyze 20 electrocardiographic (ECG) signs of left bundle branch block (LBBB) before and after septal myectomy in patients with hypertrophic cardio myopathy (HCM) and develop a criterion for proximal LBBB based on the selected signs.Material and 
L. M. Malishevsky, S. V. Zubarev, A. V. Gurshchenkov, V. K. Lebedeva, T. A. Lyubimtseva, D. S. Malishevskaya, V. V. Zaitsev, M. L. Gordeev, D. S. Lebedev   +8 more
doaj   +1 more source

Clinical implications of electrocardiographic bundle branch block in primary care

Heart, 2019
Objectives Electrocardiographic bundle branch block (BBB) is common but the prognostic implications in primary care are unclear. We sought to investigate the relationship between electrocardiographic BBB subtypes and the risk of cardiovascular (CV ...
P. Rasmussen, M. W. Skov, J. Ghouse, A. Pietersen, S. Hansen, C. Torp‐Pedersen, L. Køber, S. Haunsø, M. Olesen, J. Svendsen, J. Melgaard, C. Graff, A. Holst, J. Nielsen   +13 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Masquerading Bundle Branch Block in a Patient with Heart Failure in Nigeria

International Medical Case Reports Journal, 2020
Olumide A Akinyele, Michael O Balogun, Rasaaq A Adebayo, Oladiipo A Olanipekun, Anthony O Akintomide, Oyeronke T Williams, Obafemi S Adesanya Cardiology Unit, Department of Medicine, Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile-Ife,
Akinyele OA, Balogun MO, Adebayo RA, Olanipekun OA, Akintomide AO, Williams OT, Adesanya OS   +6 more
doaj  

Peeling off the Mask: Pseudo Myocardial Infarction Pattern on Electrocardiogram During AICD Implantation

Indian Pacing and Electrophysiology Journal, 2015
Lead induced transient right bundle branch block is not uncommon during pacemaker implantation. We describe a patient with old anterior wall myocardial infarction with severe left ventricular dysfunction presenting with recurrent ventricular tachycardia ...
Sudeep Kumar, MD, DM, FACC, FSCAI, Aditya Kapoor, DM, FACC, Nagaraja Moorthy, DM, Yash Lokhandwala, DM, FACC   +3 more
doaj   +1 more source