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Interscalene Brachial Plexus Block with Liposomal Bupivacaine versus Standard Bupivacaine with Perineural Dexamethasone: A Noninferiority Trial

Anesthesiology, 2022
Background: The interscalene nerve block provides analgesia for shoulder surgery. To extend block duration, provide adequate analgesia, and minimize opioid consumption, the use of adjuvants such as dexamethasone as well as the application of perineural ...
David H. Kim   +14 more
semanticscholar   +1 more source

Predicting the Density of Bupivacaine and Bupivacaine-Opioid Combinations

Anesthesia & Analgesia, 2002
Manipulating the density of local anesthetic solutions by using a simple formula may be clinically useful in producing optimal density solutions for spinal anesthesia under a variety of clinical conditions.
Gary M. Stocks   +2 more
openaire   +3 more sources

Bupivacaine Versus Liposomal Bupivacaine For Pain Control

Drug Research, 2017
AbstractLocal infiltrations and regional blocks have been some of the effective ways employed to manage and control post-operative pain. One of the limitations of administration of local anesthesia drugs in post-operative conditions is its inability to act for a longer period of time.
Siavash Beiranvand   +1 more
openaire   +3 more sources

The Analgesic Effects of Liposomal Bupivacaine versus Bupivacaine Hydrochloride Administered as a Transversus Abdominis Plane Block after Abdominally Based Autologous Microvascular Breast Reconstruction: A Prospective, Single-Blind, Randomized, Controlled Trial.

Plastic and Reconstructive Surgery, 2019
BACKGROUND Postoperative pain control after abdominally based autologous microvascular breast reconstruction is critical to functional recovery, patient satisfaction, and early discharge.
Austin Y. Ha   +7 more
semanticscholar   +1 more source

Liposomal Bupivacaine Transversus Abdominis Plane Block Versus Epidural Analgesia in a Colon and Rectal Surgery Enhanced Recovery Pathway: A Randomized Clinical Trial

Diseases of the Colon & Rectum, 2018
BACKGROUND: Multimodal pain management is an integral part of enhanced recovery pathways. The most effective pain management strategies have not been determined.
Daniel R Felling   +11 more
semanticscholar   +1 more source

The clinical effectiveness of epidural bupivacaine, bupivacaine with lidocaine, and bupivacaine with fentanyl for labor analgesia

Journal of Clinical Anesthesia, 1991
To examine the efficacy of bupivacaine alone and in combination with lidocaine or fentanyl for epidural analgesia during labor.Randomized, single-blind study.Labor and delivery unit at a university medical center.Forty-five primiparas requesting epidural analgesia.Following epidural placement at L3-4 interspace, patients received either bupivacaine 0.5%
Robert Goldstein   +2 more
openaire   +3 more sources

A COMPARISON OF BUPIVACAINE AND ALKALINIZED BUPIVACAINE IN BRACHIAL PLEXUS ANESTHESIA

Anesthesia & Analgesia, 1987
To define the effect of alkalinization of bupivacaine 0.5% in subclavian perivascular brachial plexus blockade, the time to onset, time to peak effect, and 6-hour regression of sensory and motor blockade were determined. Sixty physical status ASA I and II patients were randomly allocated to one of two groups and a double-blind design was used: group I (
M. D. Bedder, D. B. Craig, R. Kozody
openaire   +3 more sources

Extended release bupivacaine formulations for postoperative analgesia: an update

Current Opinion in Anaesthesiology, 2018
Purpose of review New formulations of local anesthetics with sustained release and longer duration of action are being developed to improve patient outcomes following surgery.
A. Balocco   +4 more
semanticscholar   +1 more source

New formulations of bupivacaine for the treatment of postoperative pain: liposomal bupivacaine and SABER-Bupivacaine

Expert Opinion on Pharmacotherapy, 2014
Although generally considered both safe and effective, local anesthetics are often used in conjunction with opioids postoperatively in part because of the limited duration of drug action of local anesthetics. Much interest exists in extending the duration of local anesthetics' effects, which may reduce the requirement for opioid pain medications that ...
Aaron Skolnik, Tong J. Gan
openaire   +3 more sources

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