Results 251 to 260 of about 62,498 (301)
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Drug and Alcohol Dependence, 1985
Buprenorphine is a mixed agonist-antagonist with high affinity at both mu and kappa opiate receptors. Its pharmacological profile is determined primarily by partial agonism at mu-receptors and unusually slow kinetics at these receptors. Its intrinsic activity is such that in nearly all clinical situations it is as effective an analgesic as morphine ...
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Buprenorphine is a mixed agonist-antagonist with high affinity at both mu and kappa opiate receptors. Its pharmacological profile is determined primarily by partial agonism at mu-receptors and unusually slow kinetics at these receptors. Its intrinsic activity is such that in nearly all clinical situations it is as effective an analgesic as morphine ...
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Clinical Pharmacology and Therapeutics, 1980
Buprenorphine kinetics was determined in surgical patients using radioimmunoassay. Buprenorphine was measured in the plasma of 24 patients who had received 0.3 mg buprenorphine intraoperatively. After 3 hr 10 of these patients then received a further 0.3 mg buprenorphine intravenously for postoperative pain relief, and 11 patients were given 0.3 mg ...
R E, Bullingham +3 more
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Buprenorphine kinetics was determined in surgical patients using radioimmunoassay. Buprenorphine was measured in the plasma of 24 patients who had received 0.3 mg buprenorphine intraoperatively. After 3 hr 10 of these patients then received a further 0.3 mg buprenorphine intravenously for postoperative pain relief, and 11 patients were given 0.3 mg ...
R E, Bullingham +3 more
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Injection of buprenorphine and buprenorphine/naloxone tablets in Malaysia
Drug and Alcohol Dependence, 2010Buprenorphine maintenance is efficacious for treating opioid dependence, but problems with diversion and misuse of buprenorphine (BUP) may limit its acceptability and dissemination. The buprenorphine/naloxone combination tablet (BNX) was developed to reduce potential problems with diversion and abuse.
B, Vicknasingam +3 more
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Blockade of hydromorphone effects by buprenorphine/naloxone and buprenorphine
Psychopharmacology, 2001Buprenorphine is an opioid agonist-antagonist used in the treatment of opioid dependence. Naloxone has been combined with buprenorphine to decrease the parenteral abuse potential of buprenorphine. This addition of naloxone may also confer further opioid blockade efficacy.To test the opioid blockade efficacy of sublingual buprenorphine/naloxone versus ...
Eric C, Strain +2 more
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Buprenorphine, Buprenorphine/Naloxone (Suboxone)
2023William F. Barrett, Carey Brewbaker
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Journal of the American Academy of Child & Adolescent Psychiatry, 2023
Paul E.A. Glaser +3 more
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Paul E.A. Glaser +3 more
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