Low-dose naloxone provides an abuse-deterrent effect to buprenorphine
Lynn R Webster,1 Michael D Smith,1 Cemal Unal,2 Andrew Finn3 1PRA Health Sciences, Salt Lake City, UT, USA; 2Biometrical Solutions LLC, Raleigh, NC, USA; 3BioDelivery Sciences International, Inc., Raleigh, NC, USA Abstract: In developmental research ...
Webster LR, Smith MD, Unal C, Finn A
doaj +1 more source
A Phase I Placebo-Controlled Trial Comparing the Effects of Buprenorphine Buccal Film and Oral Oxycodone Hydrochloride Administration on Respiratory Drive [PDF]
Lynn Webster, Erik Hansen
exaly +2 more sources
Economic burden and dosing trends of buprenorphine buccal film and transdermal patch in chronic low back pain [PDF]
Đurđa Vukicevic +2 more
exaly +2 more sources
Abstract Background Opioid overdose deaths have disproportionately impacted Black and Hispanic populations, in part due to disparities in treatment access. Emergency departments (EDs) serve as a resource for patients with opioid use disorder (OUD), many of whom have difficulty accessing outpatient addiction programs. However, inequities in ED treatment
Wesley C. Holland +10 more
wiley +1 more source
Recent progress in orodispersible films‐mediated therapeutic applications: A review
The current therapeutic applications of orodispersible films (ODFs) are delivered either locally or systemically for potential patients suffering from various diseases, including oral inflammation, cardiovascular diseases, pain disorders, nausea and vomiting, mood or mental disorders, erectile dysfunction and pulmonary diseases Abstract Orodispersible ...
Yu Tian +5 more
wiley +1 more source
Annual banned‐substance review—Analytical approaches in human sports drug testing 2021/2022–
Detection assays for drugs and methods of sports doping published between 2021 and 2022 are critically reviewed and evaluated in context with the Prohibited List 2022 as established by the World Anti‐Doping Agency. Abstract Also in 2021/2022, considerable efforts were invested into advancing human sports drug testing programs, recognizing and taking ...
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley +1 more source
Abstract We develop a new modeling framework for jointly modeling first prescription times and the presence of risk‐mitigating behavior for prescription drugs using real‐world data. We are interested in active surveillance of clinical quality improvement programs, especially for drugs which enter the market under an FDA‐mandated Risk Evaluation and ...
Harris Butler +3 more
wiley +1 more source
Novel pharmaceutical dosage forms of analgesics [PDF]
Among novel pharmaceutical dosage forms of analgesics, whose number and diversity are continuously increasing over the past two decades, of particular importance are transdermal opioid analgesics (fentanyl, buprenorphine) for the treatment of chronic ...
Đekić Ljiljana, Primorac Marija
doaj +1 more source
Buprenorphine initiation strategies for opioid use disorder and pain management: A systematic review
Abstract Buprenorphine possesses many unique attributes that make it a practical agent for adults and adolescents with opioid use disorder (OUD) and/or acute or chronic pain. Sublingual buprenorphine has been the standard of care for treating OUD, but its use in pain management is not as clearly defined.
Lauren A. Spreen +3 more
wiley +1 more source
Sublingual/Buccal buprenorphine and dental problems: a pharmacovigilance study
The association between dental problems and sublingual/buccal buprenorphine is unclear. We conducted an analysis of dental adverse drug reactions reported with sublingual/buccal buprenorphine in VigiBase®, the pharmacovigilance database of the World ...
François Montastruc (119809) +5 more
core +1 more source

