Results 11 to 20 of about 592 (179)
Characterization of hepatic fatty acids using magnetic resonance spectroscopy for the assessment of treatment response to metformin in an eNOS-/- mouse model of metabolic nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. [PDF]
• eNOS−/− mice fed a high fat diet develop NAFLD and accumulate intra‐abdominal and liver fat and display altered lipid composition.• Metformin results in decreased lipid accumulation and partly mitigates the development of NAFLD.• In vivo and ex vivo 1H‐MRS can quantify hepatic steatosis and response to treatment in this model.
Lavin B +10 more
europepmc +2 more sources
Abstract Environmental DNA‐based diversity studies have increased in popularity with the development of high throughput sequencing technologies. This permits the potential simultaneous retrieval of vast amounts of molecular data from many different organisms and species, thus contributing to a wide range of biological disciplines.
Rubén González‐Miguéns +11 more
wiley +1 more source
Endocannabinoid signaling in glioma
Main Points Glioma cells express cannabinoid receptors, whose pharmacological activation inhibits tumor growth in preclinical models. The biological modulation of the endocannabinoid system in glioma exerts complex, context‐dependent effects on tumor growth.
Carlos Costas‐Insua, Manuel Guzmán
wiley +1 more source
Ethiopia has a diverse topography with higher plant species composition and estimated to the higher proportion of endemic plant species. Currently, several factors drive natural forest destruction in the country, extensive agricultural land expansion triggered by increasing human population is probably the dominant force. The Dilla University Botanical
Fikadu Erenso +2 more
wiley +1 more source
Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids
Abstract Background and Aims Cholangiocarcinoma (CCA) includes a heterogeneous group of biliary cancers with a dismal prognosis. We investigated if lipid metabolism is disrupted in CCA and its role in tumor proliferation. Approach and Results The in vitro and in vivo tumorigenic capacity of five human CCA cell lines was analyzed.
Mikel Ruiz de Gauna +27 more
wiley +1 more source
Improving obesity and lipid metabolism using conjugated linoleic acid
CLA can prevent obesity and improve lipid metabolism in mice. CLA significantly decreased the body weight and reduced the serum levels of TG and TC. CLA might be involved in controlling fatty acid uptake by regulating the expression of PPARα and CD36.
Ye Sun +6 more
wiley +1 more source
Abstract The salinity barrier that separates marine and freshwater biomes is probably the most important division in biodiversity on Earth. Those organisms that successfully performed this transition had access to new ecosystems while undergoing changes in selective pressure, which often led to major shifts in diversification rates.
Rubén González‐Miguéns +13 more
wiley +1 more source
The Status of De in Romance Indefinites, Partitives and Pseudopartitives*
Abstract This paper focuses on the status of de in Romance indefinites, partitives and pseudopartitives. It argues that there is neither a ‘partitive article’ nor a ‘partitive preposition’ in syntax. De in Romance indefinites is the overt Spell‐Out of an abstract operator de that cancels the definiteness of articles and is responsible for ...
M.Teresa Espinal, Sonia Cyrino
wiley +1 more source
El Mediterráneo es una de las rutas migratorias más mortíferas del mundo y se ha convertido una vez más en centro de la polémica en relación a la actuación del buque humanitario Open Arms.
Joaquín Castillo-de-Mesa +3 more
doaj +1 more source
Como parte del proyecto I+D "Ferrofluvial 4.0 – Plan de investigación para la evaluacióny priorización de tecnologías orientadas a la electromovilidad y su penetración e impactos en elfortalecimiento de encadenamientos productivos de Colombia en sus ...
Alexander Raigoza Villada +1 more
doaj +1 more source

