Results 41 to 50 of about 51,179 (299)

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

open access: yesAdvanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni   +17 more
wiley   +1 more source

A Qualitative Analysis to Compare the Effects of Surface Machining of Conventional Denture Base Resin and Two Soft Liners: A Scanning Electron Microscopic Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2015
Introduction: The denture base acrylic resins require adjustments for various reasons. During this process there is an alteration in the surface characteristics of the denture base. Rough surfaces promote the bacterial adhesion and plaque accumulation;
Santoshi Kumari V.   +5 more
doaj   +1 more source

Geometry‐Regulated Electrode‐Wide Nucleation Patterns in Aqueous Zinc Anodes

open access: yesAdvanced Science, EarlyView.
Laser‐ablated 3D hole patterning enables geometry‐driven control of Zn deposition in aqueous batteries. The hole opening ratio (HOR) governs electrode‐wide nucleation patterns by regulating the spatial distribution of nucleation sites and the evolution of early‐stage Zn deposits.
Seyoung Han   +4 more
wiley   +1 more source

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

open access: yesAdvanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang   +18 more
wiley   +1 more source

Targeting the KAT7/H3K14ac/RAC2 Axis Mediates OXPHOS to Promote Stemness Maintenance and Malignancy in Glioblastoma

open access: yesAdvanced Science, EarlyView.
SOX2 upregulates KAT7 in glioma stem cells, where KAT7 deposits H3K14 acetylation at the RAC2 promoter to activate RAC2 transcription. RAC2‐GTP subsequently promotes PAK1/2/3 phosphorylation, increasing tricarboxylic acid cycle flux and mitochondrial respiration to support glioblastoma malignancy.
Jilong Liu   +13 more
wiley   +1 more source

Enamel Roughness Changes after Removal of Orthodontic Adhesive

open access: yesDentistry Journal, 2018
The aim of this study was to evaluate enamel roughness, quality of the enamel surfaces and time duration comparing different orthodontic adhesive removal protocols.
Felipe Weidenbach Degrazia   +4 more
doaj   +1 more source

Emerging Threat, To Iowa's Forests, Communities, Wood Industry & Economy, Bur Oak Blight, 2022

open access: yes, 2022
Bur oak (Quercus macrocarpa) is common across Iowa. In 2012, bur oak ranked second among all tree species as measured in volume of sawtimber on forest land.

core  

Decoding the Neural Circuit Underlying Context‐Cue Association in Retrieval of Morphine Reward Memory

open access: yesAdvanced Science, EarlyView.
Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi   +8 more
wiley   +1 more source

Cost/Trade-Offs of Stripper Mounted Bur Extractors from the Cotton Industry Perspective [PDF]

open access: yes, 1998
This study provides estimates of cost/trade-offs of stripper mounted bur-extractors from the producer, ginner, and the overall cotton industry perspective.
Nelson, Jeannie   +2 more
core  

Remote Ischemic Post‐Conditioning Preserves the Neurovascular Unit by Brain‐Derived Gas6 That Drives Monocyte‐Derived Macrophage Reprogramming via Axl and Vimentin after SAH

open access: yesAdvanced Science, EarlyView.
Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu   +14 more
wiley   +1 more source

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