Effects of Topical Steroids and Non-Steroidal Anti-Inflammatory Drugs on Gastrointestinal Bleeding in Rats. [PDF]
Short‐term topical ocular steroids and NSAIDs did not result in statistically significant gastrointestinal bleeding or histopathological injury in healthy rats. Limited faecal occult blood positivity was observed in some steroid‐treated animals but was not accompanied by macroscopic or microscopic evidence of mucosal damage .
Cinar H +4 more
europepmc +2 more sources
Expressions of Kisspeptin System and Ki-67 in the Reproductive Tissues of Cyclic Bitches. [PDF]
ABSTRACT Kisspeptin is a peptide that plays a pivotal role in the central regulation of gonadotropins. It is regarded as a key regulator of reproductive processes, including follicular and luteal development and endometrial remodelling. The objective of this study was to investigate the expression of KISS1, its receptor KISS1R and the proliferation ...
Korkmaz Ağaoğlu Ö +4 more
europepmc +2 more sources
Extracts From Grapefruit (Citrus paradisi) Peel via Microwave-Assisted and Conventional Extractions: Evaluation of Nosema Infection and Toxicity in Honey Bees. [PDF]
Conventional and microwave‐assisted extractions of grapefruit peels were optimized using response surface methodology (RSM) based on TPC, TFC, and antioxidant activity (DPPH). The phytochemical profiles of the two optimum extracts were characterized via HPLC before evaluating their acute and chronic toxicity, as well as their effects on honey bee (Apis
Kaya MM +4 more
europepmc +2 more sources
Optimization of Phenolic and Flavonoid Extraction From Bee Bread Using Response Surface Methodology and Central Composite Design, and Evaluation of Antimicrobial Activity. [PDF]
This study successfully optimized the extraction parameters for Turkish bee bread using Response Surface Methodology (RSM) with a Central Composite Design (CCD). Under optimized conditions (30°C, 40 mL/g ratio, 66.7% ethanol, 20 h), the recovery of total phenolics (26.86 mg GAE/g) and flavonoids was maximized.
Keyvan N +6 more
europepmc +2 more sources
A Comparative Analysis of Deep Convolutional Networks for Automated Diagnosis of Retinal Detachment in Dogs. [PDF]
ABSTRACT Objective To compare ImageNet‐pretrained deep convolutional neural networks for automated detection of retinal detachment (RD) in canine fundus photographs. Animals Studied Archived fundus images from 275 dogs. Procedures In this multicenter retrospective study, 2000 color fundus photographs (793 RD; 1207 normal) acquired between 2020 and 2025
Okur S +7 more
europepmc +2 more sources
Protective Effects of Hesperidin on Letrozole-Induced Neurotoxicity: Involvement of Oxidative Stress, Apoptotic Signaling, and Inflammation. [PDF]
Letrozole induces neurotoxicity by promoting oxidative stress, inflammation, and apoptotic signaling in the brain. Hesperidin co‐treatment mitigates these effects by restoring redox balance, suppressing pro‐inflammatory cytokines, and normalizing Bax/Bcl‐2–mediated apoptotic pathways, thereby exerting neuroprotective effects.
Ayhan İ +4 more
europepmc +2 more sources
Pharmacokinetics of Flunixin and Tolfenamic Acid in Experimental Endotoxemic Awassi Sheep. [PDF]
Endotoxemia was induced in the sheep in the group by administering 10 µg/kg of E. coli O55:B5 (LPS) toxin (via IV infusion in 30 mL of 0.9% NaCl over 30 min). The studies in the FM and TA groups were conducted according to a two‐stage crossover pharmacokinetic design, taking into account a 15‐day washout period between treatment periods ...
Altinok-Yipel F +7 more
europepmc +2 more sources
INVESTIGATION OF THE CHANGES OF LAKE SURFACE TEMPERATURES AND AREAS: CASE STUDY OF BURDUR AND EGIRDIR LAKES, TURKEY [PDF]
The world's average surface temperature has been increasing in recent decades. This situation is expected to affect aquatic systems and lakes are one of the most important aquatic systems.
N. Aslan, D. Koc-San
doaj +1 more source
Digital technology tools that are constantly developing and changing have affected the landscape architecture design and presentation styles. While traditional design methods were sufficient in the past, nowadays multipurpose computer-aided design ...
Bora BİNGÖL +2 more
doaj +1 more source
ÖzetBuaraştırma, öğrencilerin akademik yaşam içinde en çok etkilendikleri akademikfaaliyet olarak ortaya çıkan sınavlara yönelik kaygılarını ölçmeye yöneliktir.Sınav kaygısı, sınav gerginliği, zihinsel karışıklık, akademik başarı kaygısı,sınav kariyer ...
Zehra Burdur, Mümin Eser
doaj +1 more source

