Results 171 to 180 of about 1,249,019 (248)

Chironomid‐based summer temperature reconstruction of the Eemian–Weichselian transition at Lichtenberg, northern Germany

open access: yesBoreas, EarlyView.
Understanding the temperature variability of past interglacial cycles is essential to predict future climates. We present a new summer temperature reconstruction, based on the subfossil chironomid record from a small palaeolake adjacent to the Middle Palaeolithic site of Lichtenberg, northern Germany. The record spans from the Saalian late glacial over
Sonja Rigterink   +10 more
wiley   +1 more source

Inhibition of the NR4A1‐mediated cell cycle checkpoint enhances hyperplastic adipogenesis and glucose homeostasis in obesity

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The nuclear receptor NR4A1 is a critical node in transcriptional circuits for metabolic adaptation, yet its role in adipocyte progenitor (AP) fate and proliferation is unclear. We sought to define how NR4A1 governs early adipogenesis and adipose tissue plasticity.
Wanning Qiao   +13 more
wiley   +1 more source

From data chaos to physically interpretable deterministic mapping. [PDF]

open access: yesNat Commun
Jia D   +5 more
europepmc   +1 more source

Positive modulation of glucagon‐like peptide 1 (GLP‐1) receptor by endogenous haemorphins with implications in glucose metabolism and diabetes

open access: yesBritish Journal of Pharmacology, EarlyView.
Haemorphins act on GLP‐1 receptor (GLP‐1R) activity and signalling in a positive allosteric manner. This leads to potentiated GLP‐1‐mediated activity and signalling, as well as insulin synthesis, which may have implications for glucose metabolism and, thereby, diabetes and obesity. (The graph was created in BioRender.com).
Farheen Badrealam Khan   +13 more
wiley   +1 more source

Digital Professional Practice, Digital Competences and Impact on Family Support Services

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT Digital‐mediated practices in public social services require new strategies for administration, communication, assessment and intervention. Within this field, research framed under UNESCO's (2020) Media and Information Literacy model—examining digital media management and digital competence in information management, communication, digital ...
Guacimara Rodríguez   +6 more
wiley   +1 more source

Impact of global change on the distribution of mountain mammals and birds

open access: yesConservation Biology, EarlyView.
Abstract Climate change and land‐use changes are key drivers of global biodiversity loss. Many species are shifting to higher elevations or latitudes in response to global warming, often encountering unfavorable land‐use conditions during the shift. These changes can lead to reduced range size and increased extinction risks, particularly for mountain ...
Chiara Dragonetti   +5 more
wiley   +1 more source

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