Results 51 to 60 of about 39,558 (263)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Controversial Funerary Art in British Empire War Cemeteries (1917-1922)
Miranda: Revue Pluridisciplinaire du Monde AnglophoneCemeteries are places of remembrance and meditation, but also spaces for artistic expression. The shape of funerary monuments can be defined by the deceased themselves before their death or by their relatives after their death, and reflect their life and
Raphaël Willay
doaj +1 more source
Revue des Mondes Musulmans et de la Méditerranée, 2018 Our proposal questions, through socio-anthropological and empirical reflection, the public management of "the death of the emigrant" in the two communities of belonging to the emigre: the country of immigration (Saint-Étienne) and the village of origin ...
Azzedine Kinzi
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Petroleum geology of the Upper Jurassic – Lower Cretaceous of East and North-East Greenland: Blokelv-1 borehole, Jameson Land Basin: Burial and exhumation history of the Jameson Land Basin, East Greenland, estimated from thermochronological data from the Blokelv-1 core (including Appendix) [PDF]
Geological Survey of Denmark and Greenland Bulletin, 2018 Apatite fission-track analysis (AFTA) data in two Upper Jurassic core samples from the 231 m deep Blokelv-1 borehole, Jameson Land, East Greenland, combined with vitrinite reflectance data and regional AFTA data, define three palaeo-thermal episodes.
Paul F. Green, Peter Japsen
doaj
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
The memorable service and monastic humility – the history of Stanisław Konarski’s heart
Folia Historica Cracoviensia, 2016 The article concentrates on an interesting 130-year-old artefact located in the Krakow church of Piarists – the decoration of the place where Stanisław Konarski’s (1700–1773) heart was buried. Konarski was a monk of the Pious Schools in the 18th century,
Ryszard Mączyński
doaj +1 more source