Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses
AF4‐UV‐DLS‐MALS‐SAXS resolves previously inaccessible targeted lipid nanoparticle (tLNP) subpopulations that differ in size, shape, and composition. Correlation of subpopulation‐resolved biophysical properties with in vivo RNA delivery reveals that targeted placental transfection is associated with distinct tLNP subpopulations rather than ensemble ...
Hannah C. Geisler +14 more
wiley +1 more source
Study on plastic flow of conditioned soil within pressure chamber of deeply buried EPB shields tunneling through sandy stratum. [PDF]
Zhong X, Huang S, Wang H, Yun Q.
europepmc +1 more source
Can Elastomers Combine Stiffness, Toughness and Fatigue Resistance?
This review studies how the molecular and macroscopic architecture of elastomers influence their mechanical properties including: stiffness, stretchability, toughness, fatigue resistance, and damping behavior. By linking the structure to performance, it proposes design principles for advanced elastomeric systems that combine mechanical properties ...
Eva Baur, Esther Amstad
wiley +1 more source
Unearthing forensic genetics: preliminary results on the ability to generate DNA profiles from buried human biological samples. [PDF]
Gracia-de-Lucas S +3 more
europepmc +1 more source
Photoactivable Surfactant Design for In Situ Stabilization of Hydrogel Bioelectronics
Photoactivable surfactant additive enables in situ stabilization of hydrogel bioelectronics. ABSTRACT Conductive polymer hydrogels offer unique advantages for soft, stretchable biointerfaces by combining tissue‐like mechanics with high ionic conductivity.
Seungyeon Lee +11 more
wiley +1 more source
Georadar Waveform Characterization of Tunnel Lining Rear Defects and Joint Detection Method in Time and Frequency Domains. [PDF]
Liu J +7 more
europepmc +1 more source
The synergistic integration of rigid polyacrylamide (PAM) and flexible poly(N,N‐dimethylacrylamide) (PDMA) phases offers exceptional toughness to suppress lithium dendrites, simultaneously enhancing mechanical strength and ionic conductivity. ABSTRACT Gel polymer electrolytes for lithium‐metal batteries face an inherent trade‐off between mechanical ...
Hao Long +6 more
wiley +1 more source
Performance and cost-benefit analysis of an integrated earth-air heat exchanger and air handling unit system. [PDF]
Ali NB +7 more
europepmc +1 more source
Mechanistically Interpretable Artificial Intelligence for Designing Oxygen Electrocatalysts
Mechanistically interpretable artificial intelligence screens nearly seven million perovskite compositions and identifies key descriptors—d‐p hybridization and densification resistance—that govern oxygen electrocatalysis. The discovered BaCo0.8Nb0.1Zr0.1O3‐δ achieves a record 2.68 W cm−2 peak power density at 600°C with over 500 h of durable operation ...
Xueyu Hu +15 more
wiley +1 more source
Taphonomic patterns of a WWI Alpine mass grave: insights from the Italian front. [PDF]
Baranowska W +4 more
europepmc +1 more source

