Results 41 to 50 of about 133,581 (299)
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Bowls, Bobbins and Bones: Resolving the human remains crisis in British archaeology, a response [PDF]
In 2010 and 2011 a series of articles appeared in British Archaeology describing a crisis surrounding the archaeological investigation of human remains.
Sayer, Duncan
core +2 more sources
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
The work is devoted to the systematization of the materials of burial ground 3 of the archaeological complex near the village of Mayaki (ancient city of Tsarino). The materials of the excavations of some of its sites have previously been published.
Kravchenko Eduard E.
doaj +1 more source
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen +6 more
wiley +1 more source
The Cultural Construction of Childhood in Scandinavia, 3500 BC—1350AD
A set of Swedish and N orwegian burial-grounds and churchyards from the Neolithic to the Early Middle Ages (3500 BC—1350 AD) is analysed as concerns children's graves.
Stig Welinder
doaj +1 more source
In Defiance of a Stylistic Stereotype: British Crematoria, Architecture, Design and Landscape [PDF]
This paper presented a new critical reading of the crematorium, rendered ‘invisible’ by the taboo surrounding death and provided the first opportunity to disseminate this research to an international audience.
Grainger, Hilary J.
core
Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu +16 more
wiley +1 more source
Whose body? A study of attitudes towards the dead body in early modern Paris [PDF]
This chapter examines attitudes towards the dead body, as exemplified by arrangements for funerals and burials, in Paris between around 1550 and 1670.
Harding, Vanessa
core

