Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Documentation of Additional Vessels from the Johns Site (41CP12), Camp County, Texas [PDF]
The Johns site (41CP12) is a Titus phase cemetery in the Prairie Creek valley in the Big Cypress Creek stream basin of the Northeast Texas Pineywoods. The Caddo artifacts from the site are from the Robert L. Turner, Jr. and Tommy John collections.
Nelson, Bo +2 more
core +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Connected peripheries – North Danube Thrace in the 4th-3rd centuries BC. Exploring settlement patterns in the environs of the ostentatious grave of Peretu [PDF]
The following analysis emerged as an attempt to explain and contextualize a very rich grave, already historiographically notorious, with analogies equally famous, traditionally dated around the middle of the 4th c.
Maria-Magdalena ȘTEFAN, Dan ȘTEFAN
doaj
Rowland Clark and Dan Holdeman Site Human Skeletal Remains [PDF]
The Rowland Clark site was occupied by Caddoan Indian groups from approximately A.D. 1300-1600+. Twenty one of the 39 burials recovered during the Museum of the Red River excavations were assigned to the earliest McCurtain phase occupation (ca. A.D. 1300-
Loveland, Carol J.
core +1 more source
Testing the human factor: Radiocarbon dating the first peoples of the South Pacific [PDF]
Archaeologists have long debated the origins and mode of dispersal of the immediate predecessors of all Polynesians and many populations in Island Melanesia.
Anderson, Kathy +6 more
core +2 more sources
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Akinakai de tip Soloha în contextul unei noi descoperiri de la Nistrul de Jos [PDF]
In 2011, a barrow (no. 7) was excavated near the village of Purcari (Ștefan Vodă district, Republic of Moldova). The main Scythian burial contained the skeleton of a male, 30-35 years old, extended on the back, with the head to the W.
Denis TOPAL +2 more
doaj
The Southern Frontier of the Meroitic State: The View from Jebel Moya [PDF]
The site of Jebel Moya, excavated in the early twentieth century, represents arguably the largest pastoral mortuary complex in Africa. Jebel Moya is resituated in relation to the neighbouring Meroitic-era agro-pastoral settlements and the only known ...
Brass, M
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source

