Results 111 to 120 of about 94,849 (239)

Multi‐Targeting Non‐Specific Genome Engineering in Bacteria

Advanced Science, Volume 13, Issue 25, 4 May 2026.
In this study, we provide the first case to use the multi‐targeting integrase (MTI) systems in bacteria and develop a host‐independent generalizable approach, MNGE (Multi‐targeting Non‐specific Genome Engineering), for multi‐copy and random integration of metabolic genes or pathways in both Gram‐positive and Gram‐negative bacteria, which will ...
Runze Sun, Ruixiang You, Yiwen Zhou, Huiyan He, Wenfang Wang, Xudong Qu, Yinhua Lu, Lei Li   +7 more
wiley   +1 more source

A screen of Crohn's disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells. [PDF]

, 2019
Microbial metabolites are an emerging class of mediators influencing CD4+ T-cell function. To advance the understanding of direct causal microbial factors contributing to Crohn's disease, we screened 139 predicted Crohn's disease-associated microbial ...
Borneman, James, Braun, Jonathan, Bushman, Frederic, Casero, David, Chang, Yu-Ling, Harre, Nicholas, Humphries, Romney, Huttenhower, Curtis, Lewis, James, McGovern, Dermot PB, Miller, Shelley, Rossetti, Maura, Salzman, Nita, Sartor, R Balfour, Simpson, Kenneth W, Stappenbeck, Thaddeus, Sunga, Gemalene, Vlamakis, Hera, Wu, Gary, Xavier, Ramnik   +19 more
core   +1 more source

Guidelines for Reprocessing Ultrasound Transducers: 2026

Australasian Journal of Ultrasound in Medicine, Volume 29, Issue 2, May 2026.
ABSTRACT Introduction Ultrasound equipment is recognised as a potential source of harmful microorganisms which could lead to clinical infection. This highlights the importance of standardised infection prevention and control strategies for ultrasound practice across Australia and New Zealand.
Nathan Peters, Marija Juraja, Nicola Isles, Ellen Woodcock, Elissa Kennedy‐Smith, Cartan Costello, Jo McCann, Karen Mizia   +7 more
wiley   +1 more source

Prevalence and Identification of Burkholderia pseudomallei and Near-Neighbor Species in the Malabar Coastal Region of India.

PLoS Neglected Tropical Diseases, 2016
Accurate identification of pathogens with biowarfare importance requires detection tools that specifically differentiate them from near-neighbor species. Burkholderia pseudomallei, the causative agent of a fatal disease melioidosis, is one such biothreat
Bhavani V Peddayelachagiri, Soumya Paul, Sowmya Nagaraj, Madhurjya Gogoi, Murali H Sripathy, Harsh V Batra   +5 more
doaj   +1 more source

Composition and Diversity Characteristics of Gut Microbiota during the Development of Telchinia issoria (Lepidoptera: Nymphalidae)

Ecology and Evolution, Volume 16, Issue 5, May 2026.
Ramie (Boehmeria nivea) is a traditional economic crop of high commercial value, whose cultivation is threatened by the leaf‐feeding pest Telchinia issoria. This study investigated how the gut microbiota of T. issoria shifts across its larval, pupal, and adult stages using 16S rRNA amplicon sequencing. ABSTRACT Ramie (Boehmeria nivea) was a traditional
Xin Yang, Liu liu Dong, Xiao xiao Jin, Xu jie Liu, Min Gao, Jie Fang   +5 more
wiley   +1 more source

Iron Acquisition Mechanisms and Their Role in the Virulence of Burkholderia Species

Frontiers in Cellular and Infection Microbiology, 2017
Burkholderia is a genus within the β-Proteobacteriaceae that contains at least 90 validly named species which can be found in a diverse range of environments. A number of pathogenic species occur within the genus.
Aaron T. Butt, Mark S. Thomas
doaj   +1 more source

Function and Structure Relationships With Inflammation Differ in Two Chronic Suppurative Lung Diseases

Pediatric Pulmonology, Volume 61, Issue 5, May 2026.
ABSTRACT Rationale Cystic fibrosis (CF) and primary ciliary dyskinesia (PCD) are characterized by neutrophilic airway inflammation but differ in clinical features. Objectives We investigated relationships of pulmonary and systemic inflammatory markers with functional and structural lung disease.
Teresa Fuchs, Jacqueline Donovan, Andrew Ives, Samantha Irving, Gwyneth Davies, Claire Hogg, Eric Alton, Gemma Wilson, Andrew Bush, Jane C. Davies   +9 more
wiley   +1 more source

A ‘Genome‐First’ Framework for Next‐Generation Bioinputs: From Functional Mining to Rational Synthetic Microbial Communities

Environmental Microbiology, Volume 28, Issue 5, May 2026.
I propose a ‘genome‐first’ framework to collapse the phenotypic bottleneck in bioinput discovery. By integrating multi‐layered genome mining and reverse ecology, this paradigm enables the rational design of stable synthetic microbial communities for a data‐driven and sustainable agricultural bioeconomy.
Osiel Silva Gonçalves
wiley   +1 more source

Application of qPCR assays based on haloacids transporter gene dehp2 for discrimination of Burkholderia and Paraburkholderia

BMC Microbiology, 2019
Background A major facilitator superfamily transporter Dehp2 was recently shown to be playing an important role in transport and biodegradation of haloacids in Paraburkholderia caribensis MBA4, and Dehp2 is phylogenetically conserved in Burkholderia ...
Xianbin Su, Yi Shi, Ruihong Li, Zhao-Ning Lu, Xin Zou, Jiao-Xiang Wu, Ze-Guang Han   +6 more
doaj   +1 more source

AI‐Enabled Imaging for Pathogen Detection Under Stress Conditions: A Systematic Review

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT Advances in pathogen detection that incorporate artificial intelligence (AI) may capture microbial signals under challenging environmental conditions that traditional methods miss. This systematic review evaluates the application, performance, and methodological characteristics of AI‐enabled imaging for pathogen detection, including its impact
MeiLi Papa, Gillian Kuehnle, Yoo Jung (Erika) Oh, Jiyoon Yi   +3 more
wiley   +1 more source