Results 121 to 130 of about 599,112 (261)
ABSTRACT Background Primary bone diffuse large B‐cell lymphoma (PB‐DLBCL) is a rare extranodal lymphoma with heterogeneous clinical features and survival outcomes. Although most patients respond favorably to modern immunochemotherapy, reliable baseline prognostic indicators remain insufficiently defined. Methods We retrospectively analyzed 424 patients
Zhenbo Hou +7 more
wiley +1 more source
Mothers' Role Towards Management of Their Children with Burkitt's Lymphoma [PDF]
Background: Mothers of children with Burkitt lymphoma play a crucial role in the process of children’s management and full fling the children’s needs during the treatment period.
Hend Alaa Ahmed +2 more
doaj +1 more source
The Significance of cGAS‐STING Signaling in Response to Oncogenic Viruses
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Limei Guo +4 more
wiley +1 more source
Lymphoid hyperplasia and lymphoma in transgenic mice expressing the small non-coding RNA, EBER1 of Epstein-Barr virus [PDF]
Background. Non-coding RNAs have critical functions in diverse biological processes, particularly in gene regulation. Viruses, like their host cells, employ such functional RNAs and the human cancer associated Epstein-Barr virus (EBV) is no exception ...
Tsimbouri Penelope M. +15 more
core +2 more sources
pRb2/p130 protein expression and RBL2 mutation analysis in Burkitt lymphoma from Uganda [PDF]
Background: The members of the retinoblastoma protein family, pRb, p107 and pRb2 (p130), are central players in controlling the cell cycle. Whereas disturbed function of pRb is commonly seen in human cancers, it is still an open question whether pRb2 is ...
Solrun J Steine +9 more
core +2 more sources
BackgroundRichter transformation refers to the progression of an initially slow-growing small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL) into an aggressive lymphoma, typically diffuse large B-cell lymphoma (DLBCL) or Hodgkin lymphoma ...
Annaïse J. Jauch +8 more
doaj +1 more source
Primary pediatric gastrointestinal lymphoma
Background: Primary non-Hodgkin′s lymphoma (NHL) of the gastrointestinal (GI) tract is the most common extranodal lymphoma in pediatric age group. Yet, the overall incidence is very low. The rarity of the disease as well as variable clinical presentation
Ranjana Bandyopadhyay +6 more
doaj +1 more source
ABSTRACT BCL6 is a master transcriptional regulator of germinal center (GC) B cells. BCL6 is frequently translocated at the major translocation cluster (MTC) within intron 1 of the BCL6 locus, a hotspot commonly rearranged in diffuse large B cell lymphomas (DLBCLs).
Santosh Kumar Gothwal +4 more
wiley +1 more source
ABSTRACT Background Treatment intensity in older adults with lymphoma is often reduced because of frailty, comorbidities, and poor performance status (PS). Whether chronological age or delivered treatment intensity better predicts outcomes remains unclear.
Akira Mochizuki, Shotaro Hagiwara
wiley +1 more source

