Results 41 to 50 of about 27,689 (240)

African Burkitt Lymphoma: Age-Specific Risk and Correlations with Malaria Biomarkers [PDF]

, 2011
Article is also free to read on publisher website\ud \ud Abstract\ud \ud African Burkitt lymphoma is an aggressive B-cell, non-Hodgkin lymphoma linked to Plasmodium falciparum malaria.
Francis Nkrumah, Esther Kawira, Emmanuel, B., Mbulaiteye, S. M., Wabinga, H., Brubaker, G., Kishor Bhatia, Magatti, J., Robert J. Biggar, Glen Brubaker, Henry Wabinga, Nkrumah, F., Sam M. Mbulaiteye, Benjamin Emmanuel, Ogwang, M. D., Bhatia, K., Josiah Magatti, Biggar, R. J., Kawira, E., Janet Neequaye, Neequaye, J., Martin D. Ogwang   +21 more
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Regulation of pri-microRNA BIC transcription and processing in Burkitt lymphoma [PDF]

, 2007
BIC is a primary microRNA (pri-miR-155) that can be processed to mature miR-155. In this study, we show the crucial involvement of protein kinase C (PKC) and nuclear factor-kappa B (NF-kappa B) in the regulation of BIC expression upon B-cell receptor ...
van den Berg, Anke, Poppema, Sibrand, Blokzijl, T., Kroesen, Bart-Jan, van den Berg, Anke; id_orcid, Kluiver, J., de Jong, Doetje, Bouwman, E., Harms, G., Jacobs, Susan, Kluiver, J.; id_orcid   +10 more
core   +1 more source

1990–2041 Global burden of Burkitt lymphoma with 20 years forecast: A systematic analysis using the global burden disease of study of 2021

SAGE Open Medicine
Background: To investigate the trends in Burkitt lymphoma incidence, mortality, and disability-adjusted life-years, considering sex and age, from 1990 to 2021, with a 20-year forecast.
Chengyun Dou, Yidan Sang, Hongbo Zhu, Chuangjie Cao   +3 more
doaj   +1 more source

Sixth nerve palsy in sporadic Burkitt Lymphoma

American Journal of Ophthalmology Case Reports, 2019
Purpose: To describe a unique presentation of Central Nervous System Burkitt Lymphoma. Observations: A 59-year-old male presented with new onset binocular horizontal diplopia five days after initial presentation with abdominal distension, weight loss ...
Sowmya Yennam, Ashwini T. Kini, Bayan Al Othman, Andrew G. Lee   +3 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Outcomes of Patients With Burkitt Lymphoma Older Than Age 40 Treated With Intensive Chemotherapeutic Regimens [PDF]

, 2009
Burkitt lymphoma is a highly curable disorder when treated with modern intensive chemotherapy regimens. The majority of adult patients with Burkitt lymphoma in the United States are over age 40 years.
LaCasce, Ann S., Magrath, Ian T., Hoelzer, Dieter, Kelly, Jennifer L., Toothaker, Stephen R., Mead, Graham, Thomas, Deborah, Fisher, Richard I., Cheson, Bruce D., Ciminello, Lauren, Holte, Harald, Kahl, Brad S., Friedberg, Jonathan W., Van Imhoff, Gustaaf W.   +13 more
core   +1 more source

Decoding IGLL5 Mutation‐Mediated BCR Signaling: A Novel Mechanism of CD8+ T Cell Exhaustion and Ocular MALT Lymphoma Progression

Advanced Science, EarlyView.
OAML harbors recurrent IGLL5 mutations that reinforce CD79A/CD79B‐associated BCR signaling. Mechanistic analysis of the S47G and A54G variants reveals induction of CXCL10/CXCL11, enhanced CD8+ T‐cell recruitment, and exhaustion‐associated dysfunction, supporting an immune‐tolerant niche.
Andi Zhao, Haoyu Wei, Chenyu Zhou, Xinping Sun, Shuyan Da, Haiyu Liu, Zijin Wang, Hui Zhu, Shiya Shen, Qing Shao, Qi Gong, Hu Liu, Xuejuan Chen   +12 more
wiley   +1 more source

Sequential karyotyping in Burkitt lymphoma reveals a linear clonal evolution with increase in karyotype complexity and a high frequency of recurrent secondary aberrations [PDF]

, 2015
Typical Burkitt lymphoma is characterized by an IG-MYC translocation and overall low genomic complexity. Clinically, Burkitt lymphoma has a favourable prognosis with very few relapses.
Christiane Pott, Eva M. Murga Penas, Claviez, A., Klapper, W., Pott, C., Benedikt Bauer, Traulsen, A. ; https://orcid.org/, Bonn, Bettina R., Makarova, Olga, Traulsen, Arne, Kluin, P., Claviez, Alexander, Siebert, Reiner, Arne Traulsen, Sietse M. Aukema, Jutta Bradtke, Bauer, B., Rohde, Marius, Bauer, Benedikt, Bonn, B., Kluin, Philip M., Nagel, I., Aukema, S., Bradtke, Jutta, Reiner Siebert, Oschlies, I., Pott, Christiane, Rohde, M., Theil, Laura, Penas, Eva M. Murga, Philip M. Kluin, Siebert, R., Gattenloehner, Stefan, Marius Rohde, Nagel, Inga, Bettina R. Bonn, Inga Nagel, Stefan Gattenlöhner, Monika Szczepanowski, Burkhardt, B., Szczepanowski, Monika, Gattenlöhner, S., Klapper, Wolfram, Bradtke, J., Laura Theil, Alexander Claviez, Wolfram Klapper, Burkhardt, Birgit, Makarova, O., Szczepanowski, M., Oschlies, Ilske, Birgit Burkhardt, Aukema, Sietse M., Olga Makarova, Ilske Oschlies, Theil, L., Penas, E.   +56 more
core   +1 more source

SSR4 sustains Tertiary Lymphoid Structures by Regulation Quality Control of N‐linked Glycosylation During B‐cell Differentiation Into Plasmacyte in Colorectal Cancer

Advanced Science, EarlyView.
SSR4, a TRAP component induced in B cells, governs BAFFR N‐glycosylation via DDOST to sustain NF‐κB signaling, B‐cell differentiation, and TLS maturation. Its loss impairs anti‐tumor immunity, while overexpression improves antibody glycosylation and ADCC, revealing a critical regulator for cancer immunotherapy.
Wei Zhao, Youcai Zhao, Haiyang Li, Bowen Yang, Siyan Lu, Xueting Fu, Caixia Zhang, Yirong Chen, Xiaofeng Bian, Xinghua Ma, Xiaobing Yang, Bin Wang, Yuan Fang, Lulu Yang, Yelin Zhao, Shuli Zhao   +15 more
wiley   +1 more source

MicroRNA profiling in B cell non-Hodgkin Lymphoma : focus on the role of MYC [PDF]

, 2013
Non-Hodgkinlymfoon is een kwaadaardige vorm van kanker die uitgaat van de lymfeklieren. De ziekte wordt gekenmerkt door specifieke chromosoomafwijkingen en door afwijkende patronen van genexpressie.
Robertus, Jan Lukas,, Robertus, Jan Lukas   +1 more
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