Results 41 to 50 of about 599,112 (261)

Burkitt lymphoma mimicking acute pancreatitis

Autopsy and Case Reports, 2012
Burkitt lymphoma (BL) is a highly aggressive B cell lymphoma, presenting in extranodal sites or as an acute leukemia. Three clinical variants of BL are recognized: endemic BL, sporadic BL and immunodeficiency associated BL. Sporadic BL is seen worldwide,
Lívia Moscardi Bacchi, Ivan Ucella, Thiago Trolez Amancio, Marianne Castro Gonçalves, Renata Bacic Palhares, Sheila Aparecida Coelho Siqueira   +5 more
doaj   +1 more source

MDM4 Is Targeted by 1q Gain and Drives Disease in Burkitt Lymphoma.

Cancer Research, 2019
Oncogenic MYC activation promotes proliferation in Burkitt lymphoma, but also induces cell-cycle arrest and apoptosis mediated by p53, a tumor suppressor that is mutated in 40% of Burkitt lymphoma cases.
J. Hüllein, M. Słabicki, M. Rosolowski, A. Jethwa, Stefan Habringer, K. Tomska, R. Kurilov, Jun-Yan Lu, S. Scheinost, R. Wagener, Zhiqin Huang, M. Lukas, O. Yavorska, H. Helfrich, René Scholtysik, K. Bonneau, D. Tedesco, R. Küppers, W. Klapper, C. Pott, S. Stilgenbauer, B. Burkhardt, M. Löffler, L. Trumper, M. Hummel, B. Brors, M. Zapatka, R. Siebert, M. Kreuz, U. Keller, W. Huber, T. Zenz   +31 more
semanticscholar   +1 more source

Bilateral serous retinal detachments associated with burkitt lymphoma

American Journal of Ophthalmology Case Reports, 2020
Purpose: To report a case of bilateral serous retinal detachments in a patient found to have burkitt lymphoma. Observations: A patient who presented with bilateral serous retinal detachments and “B” symptoms underwent extensive workup and was found to ...
Matthew S. Wieder, Jay A. Fleischman, Saadia Rashid   +2 more
doaj   +1 more source

The association between the comprehensive Epstein-Barr virus serological profile and endemic Burkitt lymphoma

Cancer Epidemiology, Biomarkers and Prevention, 2019
Background: The discovery of Epstein–Barr virus (EBV) in Burkitt lymphoma tumors represented the first link between a virus and cancer in humans, but the underlying role of this virus in endemic Burkitt lymphoma remains unclear.
Anna E. Coghill, C. Proietti, Zhi-Wei Liu, L. Krause, Jeffery Bethony, L. Prokunina-Olsson, Adeola Obajemu, F. Nkrumah, R. Biggar, K. Bhatia, A. Hildesheim, D. Doolan, S. Mbulaiteye   +12 more
semanticscholar   +1 more source

Comprehensive Transcriptome and Mutational Profiling of Endemic Burkitt Lymphoma Reveals EBV Type-specific Differences

Molecular Cancer Research, 2017
Endemic Burkitt lymphoma (eBL) is the most common pediatric cancer in malaria-endemic equatorial Africa and nearly always contains Epstein–Barr virus (EBV), unlike sporadic Burkitt lymphoma (sBL) that occurs with a lower incidence in developed countries.
Yasin Kaymaz, C. Oduor, Hongbo Yu, Juliana A. Otieno, J. Ong'echa, A. Moormann, J. Bailey   +6 more
semanticscholar   +1 more source

Widely disseminated sporadic Burkitt lymphoma initially presented as oral manifestations in a 6-year-old boy

Journal of Oral Biology and Craniofacial Research, 2018
Burkitt lymphoma, a subtype of non-Hodgkin’s lymphoma, is an aggressive neoplasm with three variants that are endemic, sporadic, and immunodeficiency associated.
Bong-Hae Cho, Dong-Hoon Shin, Yun-Hoa Jung, Hae-Ryoun Park   +3 more
doaj   +1 more source

Continuous signaling of CD79b and CD19 is required for the fitness of Burkitt lymphoma B cells

EMBO Journal, 2018
Expression of the B‐cell antigen receptor (BCR) is essential not only for the development but also for the maintenance of mature B cells. Similarly, many B‐cell lymphomas, including Burkitt lymphoma (BL), require continuous BCR signaling for their tumor ...
Xiao-Cui He, Kathrin Kläsener, Joseena Iype, M. Becker, P. Maity, M. Cavallari, P. Nielsen, Jian-Ying Yang, M. Reth   +8 more
semanticscholar   +1 more source

Primary Breast Burkitt Lymphoma. A Case Report of a 16-Year-Old Female with a Rapidly Growing Unilateral Breast Mass

Cancer Management and Research, 2023
Yekosani Mitala,1 Brian Ssenkumba,1 Rita Nabulya,1 Francis Nsumba Kitenda,1 Habert Tumwesigye,1 Abraham Birungi,1 Richard Dratu Chau,1 Branchard Mushabe,2 Nichole Baker,3 Raymond Atwine1 1Department of Pathology, Mbarara University of Science and ...
Mitala Y, Ssenkumba B, Nabulya R, Kitenda FN, Tumwesigye H, Birungi A, Dratu Chau R, Mushabe B, Baker N, Atwine R   +9 more
doaj  

GCN5 HAT inhibition reduces human Burkitt lymphoma cell survival through reduction of MYC target gene expression and impeding BCR signaling pathways

OncoTarget, 2019
GCN5, the catalytic subunit in the acetyltransferase modules of SAGA and ATAC, functions as a coactivator of gene transcription. The SAGA complex is recruited to chromatin by transcription factors such as MYC and E2F1 to facilitate acetylation of ...
Aimee T. Farria, Lisa Maria Mustachio, Zeynep Coban Akdemir, S. Dent   +3 more
semanticscholar   +1 more source

Mechanisms of Rejection of High Grade B cell Lymphoma in Mice [PDF]

, 2008
The incidence of high grade B cell lymphoma in western countries has increased over the last decades. Improvement of conventional chemotherapy regimens has significantly contributed to prolonged 5-year survival rates which currently reach around 60 ...
Sukumar, Madhusudhanan
core   +1 more source