Expression of Glycoprotein B (gB) Correlates With Poor Prognosis in Nasopharyngeal Carcinoma
The extent of EBV lytic replication in NPC has not been fully clarified. Our study demonstrated EBV replication and release in NPC and identified a significant association between expression of the late lytic protein gB and poor prognosis. These findings suggest that late lytic gene products may contribute to tumor progression and that gB represents a ...
Shigetaka Komura +24 more
wiley +1 more source
Multiple cranial nerve palsies in immunodeficiency subtype of Burkitt lymphoma
Burkitt lymphoma is a late complication of HIV, and bilateral cranial nerve palsies are extremely rare in patients with AIDS. A twenty year old Caucasian male with known congenital HIV who had been non-adherent with anti-retroviral therapy presented with
Abbas Ali, Abhishek Kalla
doaj +1 more source
Atypical burkitt's lymphoma transforming from follicular lymphoma [PDF]
Amongst follicular lymphoma that transforms into a high-grade lymphoma, majority are diffuse large B cell lymphoma. Here we reported a rare atypical Burkitt's lymphoma transformation from an asymptomatic follicular lymphoma.
Yu Y Hwang +3 more
core +3 more sources
Neuroinflammation as a result of non‐neurotropic herpesvirus infection
Atypical memory B cells (ABCs) might stimulate autoreactive T cells to cause neuroinflammation and CNS myeloid cell activation during MS. Abstract The non‐neurotropic Epstein Barr virus (EBV) has been suggested to initiate the prodromal phase of multiple sclerosis (MS), often years before the first clinical symptoms. This review discusses mechanisms by
Christian Münz
wiley +1 more source
Background The HIV epidemic has challenged our previous understanding of endemic Burkitt's lymphoma. Despite the strong association of Burkitt's lymphoma and HIV infection in the Developed world, and against previous postulations that the cancer is due ...
Lubega Joseph
doaj +1 more source
Reversion of epigenetically mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma [PDF]
In Burkitt lymphoma/leukemia (BL), achievement of complete remission with first-line chemotherapy remains a challenging issue, as most patients who respond remain disease-free, whereas those refractory have few options of being rescued with salvage ...
Agirre-Ena, X. (Xabier) +12 more
core +1 more source
Integrating Flow Cytometry in the Diagnostic Work of HIV‐Associated Hodgkin's Lymphomas
ABSTRACT Hodgkin lymphoma (HL) is prevalent worldwide and typically presents symptoms like sudden pain, swelling, and weight loss. Classical HL (cHL) is largely treatable with modern risk‐adapted and response‐based therapy. cHL represents one of the most common malignancies occurring during the course of evolution in patients living with HIV.
Maria Santa +23 more
wiley +1 more source
Abducens nerve palsy as initial presentation of Burkitt Lymphoma during Pregnancy Post–Cesarean abducens nerve paresis and Headache [PDF]
Burkitt’s lymphoma is one of the most hematologic malignancies that involve the central nervous system. Our patient had a rare presenting symptom of lymphoma during pregnancy. It is reasonable to search for Burkitt’s lymphoma in every
Farhad Shahi +3 more
doaj
Primary Burkitt Lymphoma of the Fourth Ventricle in an Immunocompetent Young Patient
Primary Burkitt lymphoma of the central nervous system (CNS) is rare, with only few cases reported in the literature. An 18 year-old immunocompetent male presented with multiple cranial nerves palsies and was found to have a mass predominantly in the 4th
Abdulrahman Alabdulsalam +4 more
doaj +1 more source
SORBS2: A Molecular Nexus in Multisystem Diseases Through Scaffold‐Mediated Regulation
ABSTRACT Sorbin and SH3 Domain Containing 2 (SORBS2), a multifunctional scaffold protein harbouring Sorbin homology (SoHo) and Src homology 3 (SH3) domains, serves as a molecular hub in human diseases by integrating cytoskeletal remodelling, signal transduction and RNA metabolic regulation. This study systematically analyses SORBS2's molecular features,
Qiwei Jia, Yong Zhang
wiley +1 more source

