Results 21 to 30 of about 8,673 (49)

The Mla Pathway Plays an Essential Role in the Intrinsic Resistance of Burkholderia cepacia Complex Species to Antimicrobials and Host Innate Components

open access: yesJournal of Bacteriology, 2018
The outer membrane of Gram-negative bacteria acts as an effective barrier against toxic compounds, and therefore compromising this structure could increase sensitivity to currently available antibiotics.
Steve P. Bernier, Susie Son, M. Surette
semanticscholar   +1 more source

In Vitro Susceptibility of Burkholderia cepacia Complex Isolated from Cystic Fibrosis Patients to Ceftazidime-Avibactam and Ceftolozane-Tazobactam

open access: yesAntimicrobial Agents and Chemotherapy, 2018
We tested the in vitro susceptibility of ceftazidime-avibactam and ceftolozane-tazobactam and 13 other antibiotics against 91 Burkholderia cepacia complex (BCC) strains isolated from cystic fibrosis patients since 2012.
A. V. Dalem   +7 more
semanticscholar   +1 more source

Successful Treatment of Persistent Burkholderia cepacia Complex Bacteremia with Ceftazidime-Avibactam

open access: yesAntimicrobial Agents and Chemotherapy, 2018
We report our clinical experience treating a 2-month-old infant with congenital diaphragmatic hernia who experienced prolonged bacteremia with Burkholderia cepacia complex (Bcc) despite conventional antibiotic therapy and appropriate source control ...
P. Tamma   +8 more
semanticscholar   +1 more source

Burkholderia cepacia Complex Regulation of Virulence Gene Expression: A Review

open access: yesGenes, 2017
Burkholderia cepacia complex (Bcc) bacteria emerged as opportunistic pathogens in cystic fibrosis and immunocompromised patients. Their eradication is very difficult due to the high level of intrinsic resistance to clinically relevant antibiotics.
S. A. Sousa   +4 more
semanticscholar   +1 more source

In vitro activity of N-acetylcysteine against Stenotrophomonas maltophilia and Burkholderia cepacia complex grown in planktonic phase and biofilm

open access: yesPLoS ONE, 2018
Stenotrophomonas maltophilia and Burkholderia cepacia complex (Bcc) have been increasingly recognized as relevant pathogens in hospitalized, immunocompromised and cystic fibrosis (CF) patients.
S. Pollini   +11 more
semanticscholar   +1 more source

Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia.

open access: yesMicrobiological reviews, 1996
Respiratory infections with Pseudomonas aeruginosa and Burkholderia cepacia play a major role in the pathogenesis of cystic fibrosis (CF). This review summarizes the latest advances in understanding host-pathogen interactions in CF with an emphasis on ...
J. Govan, V. Deretic
semanticscholar   +1 more source

The Role of Reactive Oxygen Species in Antibiotic-Induced Cell Death in Burkholderia cepacia Complex Bacteria

open access: yesPLoS ONE, 2016
It was recently proposed that bactericidal antibiotics, besides through specific drug-target interactions, kill bacteria by a common mechanism involving the production of reactive oxygen species (ROS).
H. Van Acker   +5 more
semanticscholar   +1 more source

Biodiesel Production via Trans-Esterification Using Pseudomonas cepacia Immobilized on Cellulosic Polyurethane

open access: yesACS Omega, 2018
In this work, Pseudomonas cepacia lipase immobilized on cellulosic polyurethane was used as a catalyst for biodiesel production via trans-esterification reactions in order to provide cost-effective methods of enzyme recycling.
Li Li, Philip W. Dyer, H. Greenwell
semanticscholar   +1 more source

Burkholderia paludis sp. nov., an Antibiotic-Siderophore Producing Novel Burkholderia cepacia Complex Species, Isolated from Malaysian Tropical Peat Swamp Soil

open access: yesFrontiers in Microbiology, 2016
A novel Gram negative rod-shaped bacterium, designated strain MSh1T, was isolated from Southeast Pahang tropical peat swamp forest soil in Malaysia and characterized using a polyphasic taxonomy approach. The predominant cellular fatty acids (>10.0%) were
K. Ong   +5 more
semanticscholar   +1 more source

An outbreak of Burkholderia cepacia complex in the paediatric unit of a tertiary care hospital

open access: yesIndian Journal of Medical Microbiology, 2017
Introduction: Burkholderia cepacia complex (Bcc) has emerged as a serious nosocomial pathogen worldwide especially in patients with indwelling catheters and cystic fibrosis. Bcc is a common contaminant of pharmaceutical products.
Swapna A Mali   +4 more
semanticscholar   +1 more source

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