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Burn injuries are under-appreciated injuries that are associated with substantial morbidity and mortality. Burn injuries, particularly severe burns, are accompanied by an immune and inflammatory response, metabolic changes and distributive shock that can be challenging to manage and can lead to multiple organ failure.
Marc G Jeschke +2 more
exaly +9 more sources
The Immune and Regenerative Response to Burn Injury
Burn are diverse and complex injuries that not only have local effects but also serious systemic consequences through severe and prolonged inflammatory response.
M. Burgess +4 more
semanticscholar +1 more source
The pathogenesis and diagnosis of sepsis post burn injury
Burn is an under-appreciated trauma that is associated with unacceptably high morbidity and mortality. Although the survival rate after devastating burn injuries has continued to increase in previous decades due to medical advances in burn wound care ...
Pengju Zhang +3 more
semanticscholar +1 more source
Burn injury is debilitating and among one of the most frequently occurring traumas. Critical care improvements have allowed for increasingly positive outcomes.
Edward J. Kelly +3 more
semanticscholar +1 more source
Severity of thermal burn injury is associated with systemic neutrophil activation
Burn injuries elicit a unique and dynamic stress response which can lead to burn injury progression. Though neutrophils represent crucial players in the burn-induced immunological events, the dynamic secretion pattern and systemic levels of neutrophil ...
M. Laggner +12 more
semanticscholar +1 more source
Background Efficient re-epithelialization is important for successful skin wound healing. The proportion of epidermal stem cells (EpSCs) and dendritic epidermal T cells (DETCs) determines the extent of wound re-epithelialization, especially in large ...
Mian Liu +14 more
doaj +1 more source
To summarize new advances and research findings that relate to the treatment of burn victims.Recent advances in burn resuscitation and critical care reflect a better understanding of the acute phase pathophysiology of severe burns. Aggressive management of the unstable burn airway is always the most important clinical priority. Emphasis has been placed
Peter, Marko +4 more
openaire +3 more sources
Melatonin attenuates oxidative stress and modulates inflammatory response after experimental burn trauma [PDF]
Introduction. Thermal injury activates an inflammatory response. Melatonin possesses anti-oxidant and anti-inflammatory properties. The objective of the present work was to study melatonin effects on the inflammatory response under ...
Atanasova, Milena +3 more
core +6 more sources
ObjectiveThis study aimed to define the role of interleukine-1β (IL-1β) and tumor necrosis factor-α (TNF-α) in the expression of P311 in vascular endothelial cells (VECs) and in wound healing.MethodsDAPI staining, a CCK-8 assay, cell migration assay, and
Daijun Zhou +6 more
doaj +1 more source
Advances in single-cell RNA sequencing and its applications in cancer research
Cancers are a group of heterogeneous diseases characterized by the acquisition of functional capabilities during the transition from a normal to a neoplastic state.
Dezhi Huang +11 more
doaj +1 more source

