Results 1 to 10 of about 2,342,967 (383)
Nature Reviews Disease Primers, 2020 Burn injuries are under-appreciated injuries that are associated with substantial morbidity and mortality. Burn injuries, particularly severe burns, are accompanied by an immune and inflammatory response, metabolic changes and distributive shock that can
M. Jeschke +5 more
semanticscholar +7 more sources
Current Opinion in Anaesthesiology, 2003 To summarize new advances and research findings that relate to the treatment of burn victims.Recent advances in burn resuscitation and critical care reflect a better understanding of the acute phase pathophysiology of severe burns. Aggressive management of the unstable burn airway is always the most important clinical priority. Emphasis has been placed
Peter, Marko +4 more
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The Immune and Regenerative Response to Burn Injury
Cells, 2022 Burn are diverse and complex injuries that not only have local effects but also serious systemic consequences through severe and prolonged inflammatory response.
M. Burgess +4 more
semanticscholar +1 more source
The pathogenesis and diagnosis of sepsis post burn injury
Burns & Trauma, 2021 Burn is an under-appreciated trauma that is associated with unacceptably high morbidity and mortality. Although the survival rate after devastating burn injuries has continued to increase in previous decades due to medical advances in burn wound care ...
Pengju Zhang +3 more
semanticscholar +1 more source
Severity of thermal burn injury is associated with systemic neutrophil activation
Scientific Reports, 2021 Burn injuries elicit a unique and dynamic stress response which can lead to burn injury progression. Though neutrophils represent crucial players in the burn-induced immunological events, the dynamic secretion pattern and systemic levels of neutrophil ...
M. Laggner +12 more
semanticscholar +1 more source
Stem Cell Research & Therapy, 2022 Background Efficient re-epithelialization is important for successful skin wound healing. The proportion of epidermal stem cells (EpSCs) and dendritic epidermal T cells (DETCs) determines the extent of wound re-epithelialization, especially in large ...
Mian Liu +14 more
doaj +1 more source
Frontiers in Physiology, 2020 ObjectiveThis study aimed to define the role of interleukine-1β (IL-1β) and tumor necrosis factor-α (TNF-α) in the expression of P311 in vascular endothelial cells (VECs) and in wound healing.MethodsDAPI staining, a CCK-8 assay, cell migration assay, and
Daijun Zhou +6 more
doaj +1 more source
GDF-5 promotes epidermal stem cells proliferation via Foxg1-cyclin D1 signaling
Stem Cell Research & Therapy, 2021 Objective Epidermal stem cells (EpSCs) can self-renew, which are responsible for the long-term maintenance of the skin, and it also plays a critical role in wound re-epithelization, but the mechanism underlying EpSCs proliferation is unclear. GDF-5, also
Xiaohong Zhao +8 more
doaj +1 more source
Advances in single-cell RNA sequencing and its applications in cancer research
Journal of Hematology & Oncology, 2023 Cancers are a group of heterogeneous diseases characterized by the acquisition of functional capabilities during the transition from a normal to a neoplastic state.
Dezhi Huang +11 more
doaj +1 more source
Infection and Burn Injury [PDF]
European Burn Journal, 2022 Burn injury is debilitating and among one of the most frequently occurring traumas. Critical care improvements have allowed for increasingly positive outcomes. However, infection, whether it be localized to the site of the wound or systemic in nature, remains a serious cause of morbidity and mortality. Immune suppression predisposes the burn population
Kelly, Edward J. +3 more
openaire +2 more sources