Results 1 to 10 of about 69,791 (273)

Mathematical Model of Volume Kinetics and Renal Function after Burn Injury and Resuscitation [PDF]

Burns, 47(2), pp.371-386 (2021), 2021
This paper presents a mathematical model of blood volume kinetics and renal function in response to burn injury and resuscitation, which is applicable to the development and non-clinical testing of burn resuscitation protocols and algorithms. Prior mathematical models of burn injury and resuscitation are not ideally suited to such applications due to ...
arxiv   +1 more source

Dendritic epidermal T cells secreting exosomes promote the proliferation of epidermal stem cells to enhance wound re-epithelialization

Stem Cell Research & Therapy, 2022
Background Efficient re-epithelialization is important for successful skin wound healing. The proportion of epidermal stem cells (EpSCs) and dendritic epidermal T cells (DETCs) determines the extent of wound re-epithelialization, especially in large ...
Mian Liu, Zhihui Liu, Yunxia Chen, Shiya Peng, Jiacai Yang, Cheng Chen, Jue Wang, Ruoyu Shang, Yuanyang Tang, Yong Huang, Xiaorong Zhang, Xiaohong Hu, Yih-Cherng Liou, Gaoxing Luo, Weifeng He   +14 more
doaj   +1 more source

Effects of IL-1β and TNF-α on the Expression of P311 in Vascular Endothelial Cells and Wound Healing in Mice

Frontiers in Physiology, 2020
ObjectiveThis study aimed to define the role of interleukine-1β (IL-1β) and tumor necrosis factor-α (TNF-α) in the expression of P311 in vascular endothelial cells (VECs) and in wound healing.MethodsDAPI staining, a CCK-8 assay, cell migration assay, and
Daijun Zhou, Daijun Zhou, Tengfei Liu, Song Wang, Weifeng He, Wei Qian, Gaoxing Luo   +6 more
doaj   +1 more source

Advances in single-cell RNA sequencing and its applications in cancer research

Journal of Hematology & Oncology, 2023
Cancers are a group of heterogeneous diseases characterized by the acquisition of functional capabilities during the transition from a normal to a neoplastic state.
Dezhi Huang, Naya Ma, Xinlei Li, Yang Gou, Yishuo Duan, Bangdong Liu, Jing Xia, Xianlan Zhao, Xiaoqi Wang, Qiong Li, Jun Rao, Xi Zhang   +11 more
doaj   +1 more source

Mathematical Modeling, In-Human Evaluation and Analysis of Volume Kinetics and Kidney Function after Burn Injury and Resuscitation [PDF]

, 2021
Existing burn resuscitation protocols exhibit large variability in treatment efficacy. Hence, they must be further optimized based on comprehensive knowledge of burn pathophysiology. A physics-based mathematical model that can replicate physiological responses in diverse burn patients can serve as an attractive basis to perform non-clinical testing of ...
arxiv   +1 more source

Tunable Sulfated Alginate-based Hydrogel Platform with enhanced anti-inflammatory and antioxidant capacity for promoting burn wound repair

Journal of Nanobiotechnology, 2023
Amidst progressive advancements in tissue engineering, there has been a significant enhancement in the efficacy of anti-inflammatory hydrogel dressings, addressing a myriad of clinical challenges on wound healing.
Can Huang, Lanlan Dong, Baohua Zhao, Shurun Huang, Yifei Lu, Xiaorong Zhang, Xiaohong Hu, Yong Huang, Weifeng He, Yong Xu, Wei Qian, Gaoxing Luo   +11 more
doaj   +1 more source

Implementation of the World Health Organization Global Burn Registry: Lessons Learned

Annals of Global Health, 2022
Burn injuries are a major cause of death and disability globally; however, the true epidemiologic burden is underestimated given the limited and fragmented availability of high-quality burn injury data from many regions.
Caitlin Hebron, Kajal Mehta, Barclay Stewart, Patricia Price, Tom Potokar   +4 more
doaj   +1 more source

Strategies to enhance CAR-T persistence

Biomarker Research, 2022
Chimeric antigen receptor T (CAR-T) cell therapy has significantly improved the life expectancy for patients with refractory or relapse B cell lymphoma.
Yue Liu, Lingna An, Ruihao Huang, Jingkang Xiong, Haoyu Yang, Xiaoqi Wang, Xi Zhang   +6 more
doaj   +1 more source

GDF-5 promotes epidermal stem cells proliferation via Foxg1-cyclin D1 signaling

Stem Cell Research & Therapy, 2021
Objective Epidermal stem cells (EpSCs) can self-renew, which are responsible for the long-term maintenance of the skin, and it also plays a critical role in wound re-epithelization, but the mechanism underlying EpSCs proliferation is unclear. GDF-5, also
Xiaohong Zhao, Ruyu Bian, Fan Wang, Ying Wang, Xue Li, Yicheng Guo, Xiaorong Zhang, Gaoxing Luo, Rixing Zhan   +8 more
doaj   +1 more source

The progress of Chinese burn medicine from the Third Military Medical University—in memory of its pioneer, Professor Li Ao

Burns & Trauma, 2017
Professor Li Ao was one of the founders of Chinese burn medicine and one of the most renowned doctors and researchers of burns in China. He established one of the Chinese earliest special departments for burns at Third Military Medical University (TMMU ...
Haisheng Li, Junyi Zhou, Yizhi Peng, Jiaping Zhang, Xi Peng, Qizhi Luo, Zhiqiang Yuan, Hong Yan, Daizhi Peng, Weifeng He, Fengjun Wang, Guangping Liang, Yuesheng Huang, Jun Wu, Gaoxing Luo   +14 more
doaj   +1 more source