Results 161 to 170 of about 2,417,990 (393)

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

Advanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou, Junxian Chen, Hongxia Zhang, Lu Guo, Kevin Mai, Elijah Abraham, Dilip V. Prajapati, Yue Chang, Jing Ning, Xinchen Wang, Defeng Li, Dan‐Dan Zhang, Jianghua Sun, Rebecca A. Butcher, Lilin Zhao   +14 more
wiley   +1 more source

Preventing hot beverage scald injuries to young children [PDF]

, 2003
The focus of the research proposal was two-fold: to analyse the emphasis placed on hot beverage scald injuries to under five year olds in current public education material for parents and caregivers; and to make practical recommendations in regard to ...
Dekrout, Heidimarie, Morgans, Blair, Swain, David   +2 more
core   +1 more source

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

CHARACTERISTICS AND FEATURES OF BURN INJURY IN VICTIMS OF EMERGENCY SITUATIONS

, 2019
Shapovalov S.G., А. В. Кочетков, Dmitriev G.V., Sukhoparova E.P., Yunusova Yu.R.   +4 more
openalex   +1 more source

753 Segregation, Vulnerability, and Fundamental Causes: Understanding the Social Dimensions of Burn Injury [PDF]

, 2022
Colette Ngana
openalex   +1 more source

A Time‐Programmed Bilayer Wound Dressing for Dynamic Microenvironment Modulation and Full‐Thickness Regeneration in Diabetic Wounds

Advanced Science, EarlyView.
The Polyphenol+PDGF‐BB scaffold fabrication (Panel A) and its dual wound healing effects (Panel B: anti‐inflammation and accelerated tissue remodeling). ABSTRACT Chronic diabetic wounds suffer from dysfunctional repair programs due to accumulated advanced glycation end products (AGEs) and persistent inflammation in hyperglycemic microenvironments ...
Lei Yi, Wanqian Li, Ying Duanmu, Zihan Zhang, Shixuan Chen, Shichu Xiao, Lei Du, Miaomiao Wei   +7 more
wiley   +1 more source

Practical Management of Common Skin Injuries, Lacerations, Wounds, Trigger Fingers, and Burns [PDF]

, 2020
Ronald K. Akiki, Raman Mehrzad
openalex   +1 more source

46 Bardoxolone-methyl Microparticles Ameliorate Immune Dysfunction Following Burn and Inhalation Injury Through the NRF2/KEAP1 Axis [PDF]

, 2022
Roland F. Seim, Robert Maile, Hannah R. Hall, Shannon M. Wallet, Booker King   +4 more
openalex   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Endothelial EGLN3-PKM2 signaling induces the formation of acute astrocytic barrier to alleviate immune cell infiltration after subarachnoid hemorrhage

Fluids and Barriers of the CNS
Background Most subarachnoid hemorrhage (SAH) patients have no obvious hematoma lesions but exhibit blood–brain barrier dysfunction and vasogenic brain edema. However, there is a few days between blood‒brain barrier dysfunction and vasogenic brain edema.
Mingxu Duan, Xufang Ru, Jiru Zhou, Yuanshu Li, Peiwen Guo, Wenbo Kang, Wenyan Li, Zhi Chen, Hua Feng, Yujie Chen   +9 more
doaj   +1 more source