Results 11 to 20 of about 69,791 (273)

Synthesis of graphene oxide-quaternary ammonium nanocomposite with synergistic antibacterial activity to promote infected wound healing

Burns & Trauma, 2018
Background Bacterial infection is one of the most common complications in burn, trauma, and chronic refractory wounds and is an impediment to healing.
Tengfei Liu, Yuqing Liu, Menglong Liu, Ying Wang, Weifeng He, Gaoqiang Shi, Xiaohong Hu, Rixing Zhan, Gaoxing Luo, Malcolm Xing, Jun Wu   +10 more
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P311 Deficiency Leads to Attenuated Angiogenesis in Cutaneous Wound Healing

Frontiers in Physiology, 2017
P311 was identified to markedly promote cutaneous wound healing by our group. Angiogenesis plays a key role in wound healing. In this study, we sought to define the role of P311 in skin wound angiogenesis.
Song Wang, Xiaorong Zhang, Wei Qian, Daijun Zhou, Xunzhou Yu, Rixing Zhan, Ying Wang, Jun Wu, Weifeng He, Gaoxing Luo   +9 more
doaj   +1 more source

Nano-silver-decorated microfibrous eggshell membrane: processing, cytotoxicity assessment and optimization, antibacterial activity and wound healing

Scientific Reports, 2017
An ideal wound dressing can both promote wound healing and prevent bacterial infection. Here, we report a potential dressing prepared by incorporating an optimized concentration of silver nanoparticles (AgNPs) into the microfibers of a natural eggshell ...
Menglong Liu, Gaoxing Luo, Yuzhen Wang, Rui Xu, Ying Wang, Weifeng He, Jianglin Tan, Malcolm Xing, Jun Wu   +8 more
doaj   +1 more source

Recent advances in CAR-T cell engineering

Journal of Hematology & Oncology, 2020
Chimeric antigen receptor T (CAR-T) cell therapy is regarded as an effective solution for relapsed or refractory tumors, particularly for hematological malignancies. Although the initially approved anti-CD19 CAR-T therapy has produced impressive outcomes,
Ruihao Huang, Xiaoping Li, Yundi He, Wen Zhu, Lei Gao, Yao Liu, Li Gao, Qin Wen, Jiang F. Zhong, Cheng Zhang, Xi Zhang   +10 more
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Stability and biosafety of human epidermal stem cell for wound repair: preclinical evaluation

Stem Cell Research & Therapy, 2023
Background Cell therapy is a key technology to prevent sacrificing normal skin. Although some studies have shown the promise of human epidermal stem cells (EpiSCs), the efficacy, biosafety and quality control of EpiSC therapy have not been systematically
Xiaohong Zhao, Xue Li, Ying Wang, Yicheng Guo, Yong Huang, Dalun Lv, Mingxing Lei, Shicang Yu, Gaoxing Luo, Rixing Zhan   +9 more
doaj   +1 more source

Nano-silver-incorporated biomimetic polydopamine coating on a thermoplastic polyurethane porous nanocomposite as an efficient antibacterial wound dressing

Journal of Nanobiotechnology, 2018
Background Developing an ideal wound dressing that meets the multiple demands of good biocompatibility, an appropriate porous structure, superior mechanical property and excellent antibacterial activity against drug-resistant bacteria is highly desirable
Menglong Liu, Tengfei Liu, Xiwei Chen, Jiacai Yang, Jun Deng, Weifeng He, Xiaorong Zhang, Qiang Lei, Xiaohong Hu, Gaoxing Luo, Jun Wu   +10 more
doaj   +1 more source

METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N6-methyladenosine modification of PD-L1 mRNA in breast cancer

Molecular Cancer, 2022
Background Continual expression of PD-L1 in tumor cells is critical for tumor immune escape and host T cell exhaustion, however, knowledge on its clinical benefits through inhibition is limited in breast cancer.
Weijun Wan, Xiang Ao, Quan Chen, Yang Yu, Luoquan Ao, Wei Xing, Wei Guo, Xiaofeng Wu, Chengxiu Pu, Xueting Hu, Zhan Li, Mengwei Yao, Donglin Luo, Xiang Xu   +13 more
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An efficient antimicrobial depot for infectious site-targeted chemo-photothermal therapy

Journal of Nanobiotechnology, 2018
Background Silver and photothermal therapy (PTT) have been widely used for eradicating the drug-resistant bacteria. However, the risks of excess of silver for humans and the low efficiency of PTT still limit their in vivo therapeutic application ...
Menglong Liu, Danfeng He, Tao Yang, Wei Liu, Li Mao, Yang Zhu, Jun Wu, Gaoxing Luo, Jun Deng   +8 more
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Anti‐inflammatory hydrogel dressings and skin wound healing

Clinical and Translational Medicine, 2022
Hydrogels are promising and widely utilized in the biomedical field. In recent years, the anti‐inflammatory function of hydrogel dressings has been significantly improved, addressing many clinical challenges presented in ongoing endeavours to promote ...
Can Huang, Lanlan Dong, Baohua Zhao, Yifei Lu, Shurun Huang, Zhiqiang Yuan, Gaoxing Luo, Yong Xu, Wei Qian   +8 more
doaj   +1 more source

Weakened IL-15 Production and Impaired mTOR Activation Alter Dendritic Epidermal T Cell Homeostasis in Diabetic Mice

Scientific Reports, 2017
Diabetes is associated with impaired wound healing, which may be caused primarily by a deficiency in dendritic epidermal T cells (DETCs). In the epidermis, IL-15, IGF-1, and mTOR are known to regulate the maintenance of DETCs; however, it is unclear how ...
Zhongyang Liu, Guangping Liang, Li Gui, Yashu Li, Meixi Liu, Yang bai, Xiaorong Zhang, Xiaohong Hu, Jian Chen, Chibing Huang, Xusheng Liu, Gaoxing Luo, Jun Wu, Weifeng He   +13 more
doaj   +1 more source