Results 21 to 30 of about 2,197,281 (357)

Stability and biosafety of human epidermal stem cell for wound repair: preclinical evaluation

open access: yesStem Cell Research & Therapy, 2023
Background Cell therapy is a key technology to prevent sacrificing normal skin. Although some studies have shown the promise of human epidermal stem cells (EpiSCs), the efficacy, biosafety and quality control of EpiSC therapy have not been systematically
Xiaohong Zhao   +9 more
doaj   +1 more source

Nano-silver-incorporated biomimetic polydopamine coating on a thermoplastic polyurethane porous nanocomposite as an efficient antibacterial wound dressing

open access: yesJournal of Nanobiotechnology, 2018
Background Developing an ideal wound dressing that meets the multiple demands of good biocompatibility, an appropriate porous structure, superior mechanical property and excellent antibacterial activity against drug-resistant bacteria is highly desirable
Menglong Liu   +10 more
doaj   +1 more source

METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N6-methyladenosine modification of PD-L1 mRNA in breast cancer

open access: yesMolecular Cancer, 2022
Background Continual expression of PD-L1 in tumor cells is critical for tumor immune escape and host T cell exhaustion, however, knowledge on its clinical benefits through inhibition is limited in breast cancer.
Weijun Wan   +13 more
doaj   +1 more source

Understanding acute burn injury as a chronic disease

open access: yesBurns & Trauma, 2019
While treatment for burn injury has improved significantly over the past few decades, reducing mortality and improving patient outcomes, recent evidence has revealed that burn injury is associated with a number of secondary pathologies, many of which ...
L. Barrett   +4 more
semanticscholar   +1 more source

An efficient antimicrobial depot for infectious site-targeted chemo-photothermal therapy

open access: yesJournal of Nanobiotechnology, 2018
Background Silver and photothermal therapy (PTT) have been widely used for eradicating the drug-resistant bacteria. However, the risks of excess of silver for humans and the low efficiency of PTT still limit their in vivo therapeutic application ...
Menglong Liu   +8 more
doaj   +1 more source

Pediatric burn injuries

open access: yesInternational Journal of Critical Illness and Injury Science, 2012
Pediatric burns comprise a major mechanism of injury, affecting millions of children worldwide, with causes including scald injury, fire injury, and child abuse. Burn injuries tend to be classified based on the total body surface area involved and the depth of injury.
Sanjay M. Bhananker   +2 more
openaire   +4 more sources

Intestinal barrier dysfunction in severe burn injury

open access: yesBurns & Trauma, 2019
Severe burn injury is often accompanied by intestinal barrier dysfunction, which is closely associated with post-burn shock, bacterial translocation, systemic inflammatory response syndrome, hypercatabolism, sepsis, multiple organ dysfunction syndrome ...
Wen He, Yu Wang, Pei Wang, Feng-jun Wang
semanticscholar   +1 more source

Reconstruction and Functional Annotation of P311 Protein–Protein Interaction Network Reveals Its New Functions

open access: yesFrontiers in Genetics, 2019
P311 is a highly conserved multifunctional protein. However, it does not belong to any established family of proteins, and its biological function has not been entirely determined.
Song Wang   +10 more
doaj   +1 more source

Anti‐inflammatory hydrogel dressings and skin wound healing

open access: yesClinical and Translational Medicine, 2022
Hydrogels are promising and widely utilized in the biomedical field. In recent years, the anti‐inflammatory function of hydrogel dressings has been significantly improved, addressing many clinical challenges presented in ongoing endeavours to promote ...
Can Huang   +8 more
doaj   +1 more source

The Cutaneous Inflammatory Response to Thermal Burn Injury in a Murine Model

open access: yesInternational Journal of Molecular Sciences, 2019
Many burn interventions aim to target the inflammatory response as a means of enhancing healing or limiting hypertrophic scarring. Murine models of human burns have been developed, but the inflammatory response to injury in these models has not been well
Zabeen Lateef   +5 more
semanticscholar   +1 more source

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