Results 31 to 40 of about 69,791 (273)

NLRP3 inflammasome-mediated choroid plexus hypersecretion contributes to hydrocephalus after intraventricular hemorrhage via phosphorylated NKCC1 channels

Journal of Neuroinflammation, 2022
Background Hydrocephalus is a severe complication of intracerebral hemorrhage with ventricular extension (ICH-IVH) and causes cerebrospinal fluid (CSF) accumulation.
Zhaoqi Zhang, Qiang Tan, Peiwen Guo, Suna Huang, Zhengcai Jia, Xin Liu, Hua Feng, Yujie Chen   +7 more
doaj   +1 more source

CNN-based Speed Detection Algorithm for Walking and Running using Wrist-worn Wearable Sensors [PDF]

, 2020
In recent years, there have been a surge in ubiquitous technologies such as smartwatches and fitness trackers that can track the human physical activities effortlessly. These devices have enabled common citizens to track their physical fitness and encourage them to lead a healthy lifestyle.
arxiv   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

A one-dimensional morphoelastic model for burn injuries: stability analysis, numerical validation and biological interpretation [PDF]

, 2020
To deal with permanent deformations and residual stresses, we consider a morphoelastic model for the scar formation as the result of wound healing after a skin trauma. Next to the mechanical components such as strain and displacements, the model accounts for biological constituents such as the concentration of signaling molecules, the cellular ...
arxiv   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

Advanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im, Han‐Gil Jeong, Donghee Kim, Jimin Song, Ngoc Man Phan, Eun‐seo Choi, Young‐Min Kim, Seo‐Hyeon Jeong, Jooho Park, Inwon Park, Jaeyun Kim   +10 more
wiley   +1 more source

HDAC2 inhibits EMT-mediated cancer metastasis by downregulating the long noncoding RNA H19 in colorectal cancer

Journal of Experimental & Clinical Cancer Research, 2020
Background Emerging evidence suggests that epithelial mesenchymal transition (EMT) and epigenetic mechanisms promote metastasis. Histone deacetylases (HDACs) and noncoding RNAs (ncRNAs) are important epigenetic regulators.
Xue-ting Hu, Wei Xing, Rong-sen Zhao, Yan Tan, Xiao-feng Wu, Luo-quan Ao, Zhan Li, Meng-wei Yao, Mu Yuan, Wei Guo, Shang-ze Li, Jian Yu, Xiang Ao, Xiang Xu   +13 more
doaj   +1 more source

Joule‐Assisted Nanotherapeutic Urethral Stent (JANUS) for Spatiotemporal Theragenerative Treatment of Urethral Strictures

Advanced Functional Materials, EarlyView.
Joule‐assisted nanotherapeutic urethral stent harnesses a smart, biodegradable magnesium stent to orchestrate spatiotemporal theragenerative therapy for urethral strictures. Magnetically induced Joule heating enables on‐demand drug release and bacterial ablation, while simultaneously guiding urothelial regeneration.
Yuhyun Na, Yubeen Park, Hyun Lee, Song Hee Kim, Seojoon Bang, Hyeong Seok Kang, Chan Ho Moon, Ju Yeong Gwon, Jong Hwa Seo, Min‐Ho Kang, Soo‐Hong Lee, Gi Doo Cha, Wooram Park, Heemin Kang, Jung‐Hoon Park, Hyun‐Do Jung   +15 more
wiley   +1 more source

Impairment of insulin-stimulated glucose utilization is associated with burn-induced insulin resistance in mouse muscle by hyperinsulinemic-isoglycemic clamp [PDF]

arXiv, 2020
Burn-induced insulin resistance is associated with increased morbidity and mortality; however, the impact of burn injury on tissue-specific insulin sensitivity and its molecular mechanisms with consideration of insulin state remains unknown in rodent models.
arxiv  

Dynamic Micromechanical Characterization of 3D Printed Bone In Vitro Models Manufactured via Vat Photopolymerization

Advanced Functional Materials, EarlyView.
This study presents a novel approach to designing and fabricating high‐porosity 3D‐printed scaffolds using a customized resin. Scaffold geometry, cellular interactions, and mechanical properties are analyzed to demonstrate these engineered bone models.
Sera Choi, Elizabeth Hunt, Edward A. Shangin, Zahra Bahranifard, Emma Nguyen, Caitlyn J. Collins, Abby R. Whittington   +6 more
wiley   +1 more source

Cucurbitacin E Induces Autophagy-Involved Apoptosis in Intestinal Epithelial Cells

Frontiers in Physiology, 2020
Apoptosis plays a crucial role in maintaining the structural and functional integrity of the intestinal epithelial barrier. Autophagy mediates injury to and repair of the intestinal epithelial barrier through multiple pathways in pathophysiological ...
Huapei Song, Hehuan Sui, Hehuan Sui, Hehuan Sui, Qiong Zhang, Pei Wang, Fengjun Wang   +6 more
doaj   +1 more source