Results 51 to 60 of about 2,172,661 (342)

Stable, Easy‐to‐Handle, Fully Autologous Electrospun Polymer‐Peptide Skin Equivalent for Severe Burn Injuries

Advanced Functional Materials, EarlyView.
A bioengineered skin equivalent composed of electrospun poly(ε‐caprolactone) (PCL) and the bioactive peptide Fmoc‐FRGD is developed for severe burn treatment. This scaffold promotes full‐thickness skin regeneration by supporting cellular adhesion and integration. In‐vitro and in‐vivo studies show enhanced mechanical stability, accelerated wound closure,
Dana Cohen‐Gerassi, Marina BenShoshan, Adi Liiani, Tomer Reuveni, Offir Loboda, Moti Harats, Josef Haik, Itzhak Binderman, Yosi Shacham‐Diamand, Amit Sitt, Ayelet Di Segni, Lihi Adler‐Abramovich   +11 more
wiley   +1 more source

An appropriate Wnt/β-catenin expression level during the remodeling phase is required for improved bone fracture healing in mice

Scientific Reports, 2017
Accumulating evidence demonstrates that the Wnt/β-catenin signaling pathway plays a dominant role in bone repair. However, the role of Wnt/β-catenin signaling in the remodeling phase during bone fracture healing is currently unknown. In the present study,
Quanwei Bao, Sixu Chen, Hao Qin, Jianquan Feng, Huayu Liu, Daocheng Liu, Ang Li, Yue Shen, Yufeng Zhao, Junfeng Li, Zhaowen Zong   +10 more
doaj   +1 more source

Burn Injury Leads to Increase in Relative Abundance of Opportunistic Pathogens in the Rat Gastrointestinal Microbiome

Frontiers in Microbiology, 2017
The gastrointestinal microbiome is crucial in human health. With greater than 10 times the cell count of an individual, the gastrointestinal microbiome provides many benefits to the host.
Guangtao Huang, Kedai Sun, S. Yin, B. Jiang, Yu Chen, Y. Gong, Yajie Chen, Zichen Yang, J. Chen, Zhiqiang Yuan, Yizhi Peng   +10 more
semanticscholar   +1 more source

Ambient‐Dried MOF/Cellulose‐Based Aerogels for Atmospheric Water Harvesting and Sustainable Water Management in Agriculture

Advanced Functional Materials, EarlyView.
Ambient‐dried composite aerogels integrating MOF‐303, TEMPO‐oxidized cellulose nanofibers (TOCNF), and hygroscopic salts enable high‐performance atmospheric water harvesting (AWH), achieving competitive uptake at both low and high humidity. Enhanced with a solar‐evaporation layer, these scalable aerogels support self‐sustained plant growth in a ...
Ahmadreza Ghaffarkhah, Mahyar Panahi‐Sarmad, Sara Rostami, Orysia Zaremba, Lukas Alexander Bauman, Seyyed Alireza Hashemi, Subhajit Dutta, Pu Yang, Tianyu Guo, Feng Jiang, Stefan Wuttke, Mohammad Arjmand, Orlando J. Rojas   +12 more
wiley   +1 more source

Cardiovascular Dysfunction Following Burn Injury: What We Have Learned from Rat and Mouse Models

International Journal of Molecular Sciences, 2016
Severe burn profoundly affects organs both proximal and distal to the actual burn site. Cardiovascular dysfunction is a well-documented phenomenon that increases morbidity and mortality following a massive thermal trauma. Beginning immediately post-burn,
Ashley N Guillory, R. P. Clayton, D. Herndon, C. Finnerty   +3 more
semanticscholar   +1 more source

Bio‐Responsive Hydrogel for Targeted on‐Demand Release of a Phage Cocktail for Treatment of Pseudomonas aeruginosa Infection

Advanced Functional Materials, EarlyView.
This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao, Anna Hu, Elnaz Bavel, Chien‐Hsun Yu, Sixuan Zhang, Vera Maria Kissling, Zhihao Li, Thomas Fintan Moriaty, Katharina Maniura‐Weber, Qun Ren   +9 more
wiley   +1 more source

Central activation of TRPV1 and TRPA1 by novel endogenous agonists contributes to mechanical and thermal allodynia after burn injury

Molecular Pain, 2016
The primary complaint of burn victims is an intense, often devastating spontaneous pain, with persistence of mechanical and thermal allodynia. The transient receptor potential channels, TRPV1 and TRPA1, are expressed by a subset of nociceptive sensory ...
D. Green, S. Ruparel, Xiaoli Gao, Nikita B Ruparel, M. Patil, A. Akopian, K. Hargreaves   +6 more
semanticscholar   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

A population-based comparison study of the mental health of patients with intentional and unintentional burns

Burns & Trauma, 2018
Background A number of studies report high prevalence of mental health conditions among burn patients. However there is a need to understand differences in the temporal relationship between mental health conditions and intentional and unintentional burns
Thirthar P Vetrichevvel, Sean M Randall, Fiona M Wood, Suzanne Rea, James H Boyd, Janine M Duke   +5 more
doaj   +1 more source

Hollow‐Structured Nanorobot with Excellent Magnetic Propulsion for Catalytic Pollutant Degradation, Anti‐Bacterial and Biofilm Removal

Advanced Healthcare Materials, EarlyView.
A hollow‐structured Fe3O4@AgAu@PDA‐ZnPc nanosphere has been developed, exhibiting controllable catalytic activity and “photothermal‐photodynamic‐Ag+” coupling antibacterial characteristics. When subjected to a rotating magnetic field, these performances are uniquely enhanced by magnetic propulsion, allowing the nanosphere to function as a magnetic ...
Jing Wang, Guangjin Yu, Qunling Fang, Yunqi Xu, Jie Zhang, Ailing Hui, Shouhu Xuan, Ken Cham‐Fai Leung   +7 more
wiley   +1 more source