Results 61 to 70 of about 2,197,281 (357)

Central activation of TRPV1 and TRPA1 by novel endogenous agonists contributes to mechanical and thermal allodynia after burn injury

Molecular Pain, 2016
The primary complaint of burn victims is an intense, often devastating spontaneous pain, with persistence of mechanical and thermal allodynia. The transient receptor potential channels, TRPV1 and TRPA1, are expressed by a subset of nociceptive sensory ...
D. Green, S. Ruparel, Xiaoli Gao, Nikita B Ruparel, M. Patil, A. Akopian, K. Hargreaves   +6 more
semanticscholar   +1 more source

Bio‐Responsive Hydrogel for Targeted on‐Demand Release of a Phage Cocktail for Treatment of Pseudomonas aeruginosa Infection

Advanced Functional Materials, EarlyView.
This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao, Anna Hu, Elnaz Bavel, Chien‐Hsun Yu, Sixuan Zhang, Vera Maria Kissling, Zhihao Li, Thomas Fintan Moriaty, Katharina Maniura‐Weber, Qun Ren   +9 more
wiley   +1 more source

Burn Serum Increases Staphylococcus aureus Biofilm Formation via Oxidative Stress

Frontiers in Microbiology, 2017
Staphylococcus aureus is a common pathogen isolated from burn patients that can form biofilms on burn wounds and implanted deep vein catheters, which often leads to refractory infections or even biofilm-related sepsis.
Supeng Yin, Bei Jiang, Guangtao Huang, Yali Gong, Bo You, Zichen Yang, Yu Chen, Jing Chen, Zhiqiang Yuan, Ming Li, Fuquan Hu, Yan Zhao, Yizhi Peng   +12 more
doaj   +1 more source

Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions

Advanced Functional Materials, EarlyView.
An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park, Dong‐yup Lee, Sungsoo Lim, JangHyuk Kim, Min‐Gyu Lee, Chang Seo Park, Hyeonuk Na, Yong Eun Cho, Yun Hyeok Lee, Junsang Doh, Jeong‐Yun Sun   +10 more
wiley   +1 more source

Author Correction: Involvement of autophagy in hypoxia-BNIP3 signaling to promote epidermal keratinocyte migration

Cell Death and Disease, 2019
Following publication of the original article, it has come to our attention that the Materials and Methods section of the paper was missing. This is because this section was accidentally omitted from the final version of the manuscript when it was ...
Junhui Zhang, Can Zhang, Xupin Jiang, Lingfei Li, Dongxia Zhang, Di Tang, Tiantian Yan, Qiong Zhang, Hongping Yuan, Jiezhi Jia, Jiongyu Hu, Jiaping Zhang, Yuesheng Huang   +12 more
doaj   +1 more source

IL-15 Enhances Activation and IGF-1 Production of Dendritic Epidermal T Cells to Promote Wound Healing in Diabetic Mice

Frontiers in Immunology, 2017
Altered homeostasis and dysfunction of dendritic epidermal T cells (DETCs) contribute to abnormal diabetic wound healing. IL-15 plays important roles in survival and activation of T lymphocytes. Recently, reduction of epidermal IL-15 has been reported as
Yangping Wang, Yang Bai, Yashu Li, Guangping Liang, Yufeng Jiang, Zhongyang Liu, Meixi Liu, Jianlei Hao, Xiaorong Zhang, Xiaorong Zhang, Xiaohong Hu, Xiaohong Hu, Jian Chen, Jian Chen, Rupeng Wang, Zhinan Yin, Jun Wu, Jun Wu, Gaoxing Luo, Gaoxing Luo, Weifeng He, Weifeng He   +21 more
doaj   +1 more source

The Role of the Inflammatory Response in Burn Injury

, 2017
Burns are characterised by significant local swelling and redness around the site of injury, indicative of acute inflammation. Whilst the inflammatory response is fundamen tal to the healing process, triggering a cascade of cytokines and growth factors ...
X. Strudwick, A. Cowin
semanticscholar   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

A multifunctional platform with single-NIR-laser-triggered photothermal and NO release for synergistic therapy against multidrug-resistant Gram-negative bacteria and their biofilms

Journal of Nanobiotechnology, 2020
Background Infectious diseases caused by multidrug-resistant (MDR) bacteria, especially MDR Gram-negative strains, have become a global public health challenge.
Baohua Zhao, He Wang, Wenjing Dong, Shaowen Cheng, Haisheng Li, Jianglin Tan, Junyi Zhou, Weifeng He, Lanlan Li, Jianxiang Zhang, Gaoxing Luo, Wei Qian   +11 more
doaj   +1 more source

Functional Materials for Environmental Energy Harvesting in Smart Agriculture via Triboelectric Nanogenerators

Advanced Functional Materials, EarlyView.
This review explores functional and responsive materials for triboelectric nanogenerators (TENGs) in sustainable smart agriculture. It examines how particulate contamination and dirt affect charge transfer and efficiency. Environmental challenges and strategies to enhance durability and responsiveness are outlined, including active functional layers ...
Rafael R. A. Silva, Giulio Fatti, Emanuel Carlos, Guilherme Ferreira, Sumita Goswami, Suman Nandy, Luiz H. C. Mattoso, Elvira Fortunato, Caio G. Otoni, Rodrigo Martins   +9 more
wiley   +1 more source