Results 201 to 210 of about 1,095,170 (283)

Senescent Synovial Intimal Fibroblasts Aggravate Osteoarthritis by Regulating Macrophage Polarization and Chondrocyte Phenotype Through ANGPTL4‐α5β1 Axis

Advanced Science, EarlyView.
Senescent synovial intimal fibroblasts (SIF) are identified as key drivers of osteoarthritis. They promote M1 macrophage polarization and cartilage degeneration via the ANGPTL4–α5β1 axis, regulated by transcription factors EGR1 and ATF3. Pharmacological inhibition of this pathway alleviates disease, revealing SIF senescence as a promising therapeutic ...
Muhai Deng, Yunsheng Jiang, Zhiyu Chen, Kaiquan Chen, Na Cao, Yang Huang, Zhengxue Quan, Cheng Chen   +7 more
wiley   +1 more source

Association of Regional Agricultural Smoke Exposure With Sociodemographic Factors in Rural and Urban Communities. [PDF]

Geohealth
Slater KD, Young BN, Ford B, Adamo S, Fischer E, Gargulinski E, Henery GL, Pierce JR, Rosen Z, Sablan O, Soja A, Wiese LA, Williams CL, Magzamen S.   +13 more
europepmc   +1 more source

Engineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment

Advanced Science, EarlyView.
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu, Feiyang Xu, Zhiming Zheng, Xiaodan Yang, Fang Yang, Pei Liu, Yuankun Chen, Yunshu Yang, Junli Zhao, Peiyan Yang, Xiaojing Zheng, Xiaohong Sun, Ping Mao, Qinwen Mao, Hao Guan, Haibin Xia, Weifeng Zhang, Dan Xiao   +17 more
wiley   +1 more source

The Nallan-Nickel Effect: A Mechanistic Perspective on Burning Sensations and Lichenoid Reactions in Long-Serving Porcelain-Fused-to-Metal Restorations. [PDF]

Dent J (Basel)
Chaitanya NCSK, Hashim NT, Padmanabhan V, Islam MS, Babiker R, Mohammed R, Rahman MM.   +6 more
europepmc   +1 more source

Creating Cell‐Based Hybrid Noodles for Sustainable and Nutrient‐Balanced Diets via a Serum‐Free and Animal‐Free 3D Co‐Differentiation System

Advanced Science, EarlyView.
This study develops a 3D co‐culture and co‐differentiation system for porcine muscle stem cells (pMuSCs) and mesenchymal stem cells (pMSCs) on edible starch‐based scaffolds. The system simultaneously generates myotubes and adipocytes without using serum or chemical inducers.
Xin Guan, Luyi Wang, Wanqiang Sun, Yiwei Feng, Dandan Wang, Haohao Tang, Zhenwu Ma, Guocheng Du, Jian Chen, Jingwen Zhou   +9 more
wiley   +1 more source

Efficacy of Emblica Officinalis and Curcumin Longa, Two Significant Herbal Antioxidants, in the Management of OSMF: A Comparative Cross-sectional Study.

J Pharm Bioallied Sci
Bhambal AM, Mishra P, Saxena S, Choudhary PJ, Agarwal AK, Raj A.   +5 more
europepmc   +1 more source

Retrospective Analysis of Nail Changes and Comorbidities in Darier Disease. [PDF]

Skin Appendage Disord
Zhou MH, Zhu AY, Xing Y, Lipner SR.
europepmc   +1 more source

Encapsulating Textiles with Dynamic Covalent Networks for Sustainable and Efficient Oil Spill Cleanup

Advanced Science, EarlyView.
By encapsulating industrially relevant fabrics with dynamic imine networks, we show that the resulting composites exhibit exceptional oil absorbtion capability and chemical recyclability. It is poised for sustainable oil spill cleanup. ABSTRACT The development of high‐performance sorbents for oil spill remediation is highly desirable, which now calls ...
Changyi You, Ping Yu, Haiyue Wang, Qirui Huang, Wei Hong, Cai Liu, Qinchao Sun, Yan Wang, Youwei Ma, Zuming Hu   +9 more
wiley   +1 more source

Burning mouth syndrome: updates on pathogenesis and diagnostic algorithms. [PDF]

J Oral Facial Pain Headache
Canfora F, Calabria E, Armogida NG, Ottaviani G, Mignogna MD, Spagnuolo G, Adamo D.   +6 more
europepmc   +1 more source