Results 151 to 160 of about 40,927 (287)

Characterisation and Prognostic Implication of Cholestasis After Burn Injury

Alimentary Pharmacology &Therapeutics, EarlyView.
In 532 burn ICU patients, we quantified trajectories of cholestasis markers and validated burn‐associated cholestasis definitions. Bilirubin dynamics, particularly hyperbilirubinemia ≥ 2× ULN within 14 days, independently predicted excess in‐hospital and overall mortality beyond burn and critical‐illness severity, identifying a high‐risk subgroup after
Lorenz Semmler, Georg Semmler, Andreas Langa, Sebastian Rihl, Sebastian Hofstetter, Melissa‐Patricia Mateas, Kevin Dilmen, Anton Borger, Paul Supper, Patrick Haselwanter, Emina Halilbasic, Christian Zauner, Albert Stättermayer, Gerald Ihra, Christine Radtke, Mathias Anselm Schneeweiss‐Gleixner, Michael Trauner   +16 more
wiley   +1 more source

Investigating risk factors and antibiotic resistance of bloodstream infections causing Klebsiella pneumoniae in burn patients. [PDF]

Medicine (Baltimore)
Wang L, Li Y, Zhang J, Xiao H, Xia C.
europepmc   +1 more source

Toxicokinetic modelling of the synthetic cannabinoid 5F‐MDMB‐P7AICA and its main metabolite in pigs following pulmonary administration

British Journal of Clinical Pharmacology, EarlyView.
Aims Since their emergence on the drug market, synthetic cannabinoids (SC) are still gaining increasing importance in forensic toxicology. The representatives of the so‐called new psychoactive substances have in common that they have not undergone preclinical safety studies. Hence, knowledge on toxicokinetic (TK) data is sparse.
Adrian A. Doerr, Christiane Dings, Omar Zaher, Frederike Nordmeier, Nadja Walle, Matthias W. Laschke, Michael D. Menger, Peter H. Schmidt, Markus R. Meyer, Thorsten Lehr, Nadine Schaefer   +10 more
wiley   +1 more source

Butane-related severe burns in adolescents: high risk of early tracheostomy in a Northeast China cohort analysis. [PDF]

Crit Care
Zhang XH, Yu JA.
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Potential Prognostic Parameters from Patient Medical Files for Inhalation Injury Presence and/or Degree: A Single-Center Study. [PDF]

Eur Burn J
Prinsloo TK, Kleintjes WG, Najaar K.
europepmc   +1 more source

Cytochrome P450 1A1 influences obesity‐induced pulmonary hypertension

British Journal of Pharmacology, EarlyView.
Background and Purpose The contribution of obesity to pulmonary arterial hypertension (PAH) pathophysiology remains poorly understood. Adipose tissue synthesises estrogens via cytochrome P450 (CYP) 19A1 (aromatase), whereas circulating estrogens are metabolised in the lung by CYP1A1.
Joshua P. Dignam, Smriti Sharma, Gregor Aitchison, Ayman Gebril, Ioannis Stasinopoulos, Sofia Laforest, Chelbi Coyle, Ruth Andrew, Natalie Z. M. Homer, Sébastien Bonnet, Sandra Breuils‐Bonnet, Martin Wabitsch, Margaret R. MacLean   +12 more
wiley   +1 more source

Short-Term Outcomes of Burn Patients: a Tertiary Hospital's Four-Year Experience. [PDF]

Maedica (Bucur)
Ungureanu A, Marinescu SA, Giuglea C, Trandafir AN, Marinescu MC, Gavrila IM, Rugina AI, Gheorghiu-Branaru MC.   +7 more
europepmc   +1 more source

Chronic hepatitis in horses with persistent equine hepacivirus infection

Equine Veterinary Journal, EarlyView.
Abstract Background Equine hepacivirus (EqHV) is closely related to hepatitis C virus (HCV), which causes persistent infection and chronic hepatitis in people. Information on persistent EqHV infection and hepatitis is limited. Objectives To report 19 cases of chronic hepatitis and persistent EqHV infection.
Mason C. Jager, Daniela Luethy, Samantha Shallop, Jessica Cathcart, Thomas J. Divers, Jean‐Yin Tan, Erin McConachie Beasley, Philip Johnson, Laurence Leduc, Claire Smith, Camilla Anne Jamieson, K. Gary Magdesian, Gerlinde R. Van de Walle, Joy E. Tomlinson   +13 more
wiley   +1 more source

A predictive formula for the indication of airway management in burn patients. [PDF]

Eur J Med Res
Zhu W, Liu W, Zhang Y, Luo W, Li N, Li Y, Xie X, Yuan Z, Luo G, Li H.   +9 more
europepmc   +1 more source