Results 41 to 50 of about 38,946 (278)

Survival and analysis of prognostic factors for severe burn patients with inhalation injury: based on the respiratory SOFA score

BMC Emergency Medicine, 2023
Background It is important to determine the severity of inhalation injury in severely burned patients. The oxygenation index PaO2/FiO2(PF) ratio is a key clinical indicator of inhalation injury.
Qiang Ji, Jun Tang, Shulian Li, Junjie Chen   +3 more
doaj   +1 more source

Thermal Burns and Smoke Inhalation Injuries [PDF]

, 2015
In this pathophysiology paper, the reader is presented with a profile of an elderly patient who recently suffered thermal burns and smoke inhalation injuries as a result of a nursing home fire.
Cox, Anna
core   +1 more source

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

Advanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma, Xing Li, Minxuan Jing, Zezhong Yang, Jiale He, Jianpeng Li, Xiao Liang, Yunzhong Jiang, Rou Huang, Yuanquan Zhang, Yuanchun Pu, Jiawei Xiu, Yutong Chen, Kaibo Mi, Pu Zhang, Lei Wang, Jinhai Fan   +16 more
wiley   +1 more source

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

Animal Models and Experimental Medicine, EarlyView.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang, Keru Li, Lei Tan, Wei Chen, Shan Gao, Chenyang Liu, Shuo Pan, Jiayue He, Ning Liu, Gefan Wan, Wei Dong, Weining Kong, Bin Shen, Xiaolong Qi, Yuanwu Ma   +14 more
wiley   +1 more source

Characteristics of burn deaths from 2003 to 2009 in a burn center: A retrospective study

Burns & Trauma, 2013
Mortality remains one of the most important end-point quality control parameters to evaluate a burn care system. We retrospectively reviewed the characteristics and multiple organ dysfunction syndrome (MODS) patterns of burn deaths in our center from ...
Jian Chen, Hong Yan, Gaoxing Luo, Qizhi Luo, Xiaolu Li, Jiaping Zhang, Zhiqiang Yuan, Daizhi Peng, Yizhi Peng, Jianian Hu, Jun Wu   +10 more
doaj   +1 more source

Characteristics of burn injury during COVID-19 pandemic in Tokyo: A descriptive study

Burns Open, 2021
Introduction: Coronavirus disease 2019 (COVID-19) has drastically changed everyday life worldwide. This study aimed to determine how COVID-19 affected the characteristics and outcomes of patients with severe burn injury by examining a city-wide burn ...
Ryo Yamamoto, Yukio Sato, Kazuki Matsumura, Junichi Sasaki   +3 more
doaj   +1 more source

The Impact of Face and Neck Burns on Respiratory Complications and Mortality

European Burn Journal
Face and neck burns present significant clinical challenges due to their proximity to the airway, predisposing patients to inhalation injuries and subsequent respiratory complications.
Rares-Adrian Giurgiu, Eliza-Maria Bordeanu-Diaconescu, Andreea Grosu-Bularda, Adrian Frunza, Sabina Grama, Raducu-Andrei Costache, Carina-Ioana Cristescu, Tiberiu-Paul Neagu, Ioan Lascar, Cristian-Sorin Hariga   +9 more
doaj   +1 more source

A prospective analysis of risk factors for pediatric burn mortality at a tertiary burn center in North India

Burns & Trauma, 2017
Background None of the available mortality predicting models in pediatric burns precisely predicts outcomes in every population. Mortality rates as well as their risk factors vary with regions and among different centers within the regions.
Amol Dhopte, Rahul Bamal, Vinay Kumar Tiwari   +2 more
doaj   +1 more source

Hypothermia in acutely presenting burn injuries to a regional burn service: The incidence and impact on outcome

Burns Open, 2021
Background: Hypothermia in burns has been associated with increased mortality when adjusting for burn severity. This study looks at the incidence of hypothermia among burn patients presenting acutely to the Pietermaritzburg Burn Service and its impact on
M.R. Lukusa, N.L. Allorto, S.L. Wall
doaj   +1 more source

Inhalation injury: epidemiology, pathology, treatment strategies [PDF]

, 2013
Lung injury resulting from inhalation of smoke or chemical products of combustion continues to be associated with significant morbidity and mortality. Combined with cutaneous burns, inhalation injury increases fluid resuscitation requirements, incidence ...
David J Dries, Frederick W Endorf
core   +1 more source