Results 31 to 40 of about 1,229,579 (301)

Suppression of overactivated immunity in the early stage is the key to improve the prognosis in severe burns

Frontiers in Immunology
BackgroundSevere burns can lead to systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) due to inflammation-immunity dysregulation. This study aimed to identify key immune-related molecules and potential drugs for
Yang Xiang, Bo-han Pan, Jin Zhang, Ji-qiu Chen, He Fang, Qun Wang, Lin-hui Li, Tian-sheng Chen, Jia-xin Chen, Jia-xin Chen, Chan Li, Xing-feng Zheng, Shi-hui Zhu   +12 more
doaj   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

A Comparative Study of the ReCell® Device and Autologous Spit-Thickness Meshed Skin Graft in the Treatment of Acute Burn Injuries. [PDF]

, 2018
Early excision and autografting are standard care for deeper burns. However, donor sites are a source of significant morbidity. To address this, the ReCell® Autologous Cell Harvesting Device (ReCell) was designed for use at the point-of-care to prepare a
Cairns, Bruce A, Carter, Jeffrey E, Cruse, C Wayne, Dissanaike, Sharmila, Feldman, Michael J, Foster, Kevin N, Greenhalgh, David G, Griswold, John A, Hickerson, William L, Holmes Iv, James Hill, Hwang, James, Jordan, Marion H, King, Booker T, Molnar, Joseph A, Mozingo, David W, Palmieri, Tina L, Peck, Michael D, Smith, David J, Sood, Rajiv   +18 more
core   +1 more source

77 METHODS FOR IDENTIFYING FILIPINO GENDER MINORITIES AND MENTAL HEALTH RISKS IN ELECTRONIC HEALTH RECORDS

Journal of Clinical and Translational Science, 2023
OBJECTIVES/GOALS: Aim 1: To explore methodologies to identify gender minorities, and Filipinos, separately, in an electronic health record system. Aim 2: To characterize the similarities and differences in demographic, socioeconomic, and mental health of
Charlene Bumanglag, Stephanie Mikhail, Renee Rumler, James Davis, Deborah Goebert   +4 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Not Burns – Dunbar! [PDF]

, 2016
No abstract ...
Riach, Alan
core  

Myristoylated Cathelicidin-DM Fused With ANG1-7: A Novel Self-Assembling Antimicrobial Peptide for the Treatment and Mechanism of Diabetic Infected Wounds

Journal of Diabetes Research
Diabetic wounds, due to severe vascular dysfunction, persistent inflammatory responses, and susceptibility to microbial infections, exhibit delayed healing and pose a significant challenge to human health.
Rongqin Feng, Peng Wang, Li Fan, He Lu, Danna Yao, Panpan Sun, Zhonghua Liu, Fu Han, Xiaozhi Bai, Xuekang Yang, Juntao Han   +10 more
doaj   +1 more source

Epidemiology and acute management of high tension electrical burns in a rural-based medical college

Амбулаторная хирургия, 2023
Introduction. Electrical burns are one of the most common causes of burns besides flame burns and scalds. High tension electrical burns lead to greater morbidity and mortality.
S. Jain, Ch. Singla, S. Toor, D. J. Bhatti, P. Gupta   +4 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Introduction: new developments in Robert Burns bibliography [PDF]

, 2017
Introduces four talks given at the National Library of Scotland on March 16, 2017, at a workshop on New Developments in Robert Burns Bibliography, jointly convened by Robert Betteridge of the National Library and by Prof. Carruthers, as general editor of
Carruthers, Gerard
core   +1 more source