Results 41 to 50 of about 280,486 (313)

Global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis burden, 1990–2021

Arthritis Care &Research, Accepted Article.
Objective This study examined the global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis (OA) burden from 1990 to 2021. Methods Age‐standardized years lived with disability rate for site‐specific OA across 204 countries/territories were obtained from the Global Burden of Diseases Study (GBD) 2021.
Haowei Chen, Lei Si, David J Hunter, Lei Zhang, Zhe‐Sheng Chen, Xiaomeng Wang, Vicky Duong, Zhounan Zhou, Peihua Cao, Han Cen, Su'an Tang, Tianyu Chen, Houjun Xue, Zhaohua Zhu, Changhai Ding   +14 more
wiley   +1 more source

AMPK activation eliminates senescent cells in diabetic wound by inducing NCOA4 mediated ferritinophagy

Molecular Medicine
Background Diabetic wounds are one of the long-term complications of diabetes, with a disordered microenvironment, diabetic wounds can easily develop into chronic non-healing wounds, which can impose a significant burden on healthcare.
Mengqian Liu, Xuerong Wei, Zijun Zheng, Erlian Xie, Qiuyi Yu, Yanbin Gao, Jun Ma, Lei Yang   +7 more
doaj   +1 more source

A novel nano-emulsion cream of casein isolated from raw milk for thermal and acid burn wounds [PDF]

Brazilian Journal of Pharmaceutical Sciences
Traditionally, raw cow milk has been employed to treat acid and thermal burns due to its antibacterial, antibiotic, and antifungal properties. It also aids in preventing scarring and alleviating burn-related skin discomfort.
Shivani Shrivastava, Saumya Das, Chanchal Sharma, Archna Singh, Sanjita Das, Manas Kumar Das, Pankaj Kumar Tyagi, Navneet Khurana   +7 more
doaj   +1 more source

Demographic recruitment bias of adults in United States randomized clinical trials by disease categories between 2008 to 2019: a systematic review and meta-analysis

Scientific Reports, 2023
To promote health equity within the United States (US), randomized clinical trials should strive for unbiased representation. Thus, there is impetus to identify demographic disparities overall and by disease category in US clinical trial recruitment, by ...
Ilana Buffenstein, Bree Kaneakua, Emily Taylor, Masako Matsunaga, So Yung Choi, Enrique Carrazana, Jason Viereck, Kore Kai Liow, Arash Ghaffari-Rafi   +8 more
doaj   +1 more source

To burn or not to burn: governance of wildfires in Australia

Ecology and Society
Globally, wildfires are increasing in extent, frequency, and severity. Although global climate change is a major driver and large-scale governance interventions are essential, focusing on governance at smaller scales is of great importance for fostering resilience to wildfires.
Clement, Sarah, Garmestani, Ahjond, Beckwith, Jo Ann, Cannon, Pele J.   +3 more
openaire   +4 more sources

LOXHD1 and RHOB Expression by Monocytes Predicts Progressive Systemic Sclerosis associated Interstitial Lung Disease

Arthritis Care &Research, Accepted Article.
Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla, Robert Lafyatis, Kevin F Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J Kass   +13 more
wiley   +1 more source

Evolution of burn injury management in KATH, Kumasi-Ghana, 1954–2017

Burns Open, 2018
Introduction: Burns management worldwide has evolved over the decades with remarkable improvement, especially in High Income Countries. Knowledge about the various eras; challenges encountered, strategies to overcome them and other vital information are ...
Pius Agbenorku
doaj   +1 more source

Physician Referral Patterns to Physical Therapists for Managing Knee Osteoarthritis: A Retrospective Analysis of Electronic Health Records from an Integrated Health System

Arthritis Care &Research, Accepted Article.
Objectives This study aims to describe the frequency and timing of physician referrals to physical therapists (PT) and other treatments prescribed over 12 months in patients with recent onset of knee osteoarthritis (KOA). The study also aims to identify determinants of early PT referrals.
Samannaaz S. Khoja, Joel M. Stevans, Gustavo J. Almeida, Clair Smith, Janet K. Freburger   +4 more
wiley   +1 more source

Exosome-Derived microRNA: Potential Target for Diagnosis and Treatment of Sepsis

Journal of Immunology Research
Exosome-derived microRNAs (miRNAs) are emerging as pivotal players in the pathophysiology of sepsis, representing a new frontier in both the diagnosis and treatment of this complex condition.
Yujie Xiao, Yixuan Yuan, Dahai Hu, Hongtao Wang   +3 more
doaj   +1 more source

Prevalence, determinants and outcomes of low disease activity and remission attainment in SLE patients with clinically active disease

Arthritis Care &Research, Accepted Article.
Objectives This study aimed to identify the frequency and determinants of Lupus Low Disease Activity State (LLDAS) and Definition of Remission in SLE (DORIS‐remission) attainment in systemic lupus erythematosus (SLE) patients with clinically active disease, and the frequency and determinants of flare and damage accrual after target attainment.
Yanjie Hao, Dylan Hansen, Rangi Kandane‐Rathnayake, Worawit Louthrenoo, Yi‐Hsing Chen, Jiacai Cho, Aisha Lateef, Laniyati Hamijoyo, Shue Fen Luo, Yeong‐Jian Jan Wu, Sandra Navarra, Leonid Zamora, Zhanguo Li, Sargunan Sockalingam, Yasuhiro Katsumata, Masayoshi Harigai, Zhuoli Zhang, Madelynn Chan, Jun Kikuchi, Tsutomu Takeuchi, Sang‐Cheol Bae, Fiona Goldblatt, Sean O'Neill, Kristine (Pek Ling) Ng, Annie Law, BMDB Basnayake, Nicola Tugnet, Sunil Kumar, Cherica Tee, Michael Tee, Naoaki Ohkubo, Yoshiya Tanaka, Shirley Chan, CS Lau, Vera Golder, Alberta Hoi, Shereen Oon, Eric Morand, Mandana Nikpour, for the Asia Pacific Lupus Collaboration   +39 more
wiley   +1 more source