Results 51 to 60 of about 363,799 (294)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

CME Expansion as the Driver of Metric Type II Shock Emission as Revealed by Self-Consistent Analysis of High Cadence EUV Images and Radio Spectrograms

, 2013
On 13 June 2010, an eruptive event occurred near the solar limb. It included a small filament eruption and the onset of a relatively narrow coronal mass ejection (CME) surrounded by an extreme ultraviolet wave front recorded by the Solar Dynamics ...
Caroubalos, C., Hillaris, A., Kontogeorgos, A., Kouloumvakos, A., Moussas, X., Patsourakos, S., Preka-Papadema, P., Tsitsipis, P., Vourlidas, A.   +8 more
core   +1 more source

Extreme-mass-ratio bursts from the Galactic Centre

, 2012
Submitted to the Proceedings of the 9th LISA Symposium ...
Berry, Christopher P. L., Gair, Jonathan R.   +1 more
openaire   +2 more sources

A Comprehensive Overview of the Clinical, Electrophysiological, and Neuroimaging Features of BPAN: Insights From a New Case Series

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Neurodegeneration with brain iron accumulation (NBIA) comprises a genetically and clinically heterogeneous group of rare neurological disorders characterized particularly by iron accumulation in the basal ganglia. To date, 15 genes have been associated with NBIA.
Seda Susgun, Ozgu Kizek, Sibel Aylin Ugur Iseri, Ibrahim Kamaci, Ayse Deniz Elmali, Pinar Iscen, Berfin Gulkaya Guzel, Gul Yalcin Cakmakli, Bulent Elibol, Berril Donmez, Raif Cakmur, Pinar Topaloglu, Turkish NBIA Study Group, Abdullah Acar, Ahmet Acarer, Arzu Karabay, Asuman Ali, Ayla Barlas, Aysegul Gunduz, Banu Ozen Barut, Baris Baslo, Bilge Kocer, Bilgehan Mus, Birsen Karaman, Burcu Gokce Cokal, Cem Ismail Kucukali, Cenk Akbostanci, Ceyhun Sayman, Cagla Turan, Dilek Ince Gunal, Ebru Bilge Dirik, Ebru Erzurumluoglu, Elif Kocasoy Orhan, Enes Demiryurek, Emrah Yucesan, Ercan Kose, Erdem Tuzun, Esen Saka Topcuoglu, Esra Okuyucu, Fatma Betul Ozdilek, Feriha Ozer, Gencer Genc, Gozde Unal, Gulay Kenangil, Gullu Tarhan, Gunes Kiziltan, Halil Onder, Hamit Genc, Hasmet Hanagasi, Hatice Yuksel, Hulya Apaydin, Koray Kirimtay, Mehmet Guney Senol, Melisa Kilic, Meltem Demirkiran, Mert Karaca, Miray Erdem, Muhammet Bilgehan Mus, Murat Gultekin, Nalan Capan, Nazan Karagoz Sakalli, Nazli Basak, Nihan Hande Akcakaya, Ozan Ezer, Ozge Uygun, Ozge Yilmaz Kuspeci, Ozgur Oztop Cakmak, Pervin Iseri, Petek Ballar Kirmizibayrak, Pinar Elkoca, Recep Alp, Remzi Yigiter, Rezzak Yilmaz, Sadika Ozdemir, Selda Keskin, Selen Ilhan Alp, Selen Soylu, Serdar Ceylaner, Serhat Ozkan, Sevda Erer Ozbek, Sevgin Gundogan, Sevil Yasufli, Sezin Alpaydin Baslo, Sibel Ertan, Sultan Cagirici, Seyma Aykac, Vuslat Yilmaz, Yaprak Secil, Yasar Kutukcu, Yeliz Ciftci, Yesim Sucullu Karadag, Yildiz Değirmenci, Zeliha Matur, Nerses Bebek, Murat Emre, Zuhal Yapici   +95 more
wiley   +1 more source

Mechanism of Rock Burst Revealed by Numerical Simulation and Energy Calculation

Shock and Vibration, 2020
We propose a new computational method to calculate the storage elastic energy value of surrounding rocks based on numerical simulation and theoretical calculation.
Wenlong Zhang, Nianjie Ma, Ji Ma, Chen Li, Jianju Ren   +4 more
doaj   +1 more source

Burst-and-coast swimmers optimize gait by adapting unique intrinsic cycle

Communications Biology, 2021
Li et al. use experimental observations of red-nose tetrafish and mathematical simulations to model the burst-and-coast swimming regime. This study shows that in order to sustain the necessary speed, fish adopt a unique intrinsic cycle by modifying the ...
Gen Li, Intesaaf Ashraf, Bill François, Dmitry Kolomenskiy, Frédéric Lechenault, Ramiro Godoy-Diana, Benjamin Thiria   +6 more
doaj   +1 more source

Route selection of deep-lying and hard rock tunnel in the Sichuan-Tibet Railway based on rock burst risk assessment

Shuiwen dizhi gongcheng dizhi, 2021
The large terrain undulations and strong regional geological structures are the typical characteristics along the Sichuan-Tibet Railway. The high ground stress problem in tunnel construction is extremely complex, especially the rockburst problem in deep ...
Shikuo CHEN, Hanrui LI, Hang ZHOU, Xingqiang CHEN, Tong LIU   +4 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Composite Electrospun Fibers Containing Optimized B‐ and Cu‐Doped Bioactive Glass Sol‐Gel Particles for Potential Soft Tissue Engineering Applications

Advanced Engineering Materials, EarlyView.
This article describes the preparation and characterization of poly(ε‐caprolactone) electrospun composite fibers incorporating sol‐gel‐derived bioactive glass particles doped with B and Cu. Scanning electron microscopy, energy‐dispersive X‐ray spectroscopy, Fourier‐transform infrared spectroscopy, contact angle, acellular bioactivity, mechanical and ...
Elisa Piatti, Marta Miola, Liliana Liverani, Paolo Sartori, Enrica Verné, Aldo R. Boccaccini   +5 more
wiley   +1 more source

The effect of galaxy mass ratio on merger--driven starbursts

, 2007
We employ numerical simulations of galaxy mergers to explore the effect of galaxy mass ratio on merger--driven starbursts. Our numerical simulations include radiative cooling of gas, star formation, and stellar feedback to follow the interaction and ...
Avishai Dekel, Barton E. J., Broeils A. H., Covington M., de Jong R. S., Ellison S. L., Joel R. Primack, Joseph R. D., Kormendy J., Lacey C., Patrik Jonsson, Rachel S. Somerville, Rocha M., Scannapieco C., Schweizer F., Struck C., T. J. Cox   +16 more
core   +1 more source