Results 241 to 250 of about 59,149 (303)

Human Foetal Neuroblasts Exhibit BK Channel‐Dependent Membrane Voltage Oscillations upon Depolarization

open access: yesAdvanced Science, EarlyView.
Primary cultures of neuroblasts isolated from the nucleus basalis of Meynert of 12‐weeks‐old human foetuses were prepared. Whole‐cell patch‐clamp recordings were performed by injecting a depolarizing stimulus current (+500 pA; 500 ms), and the membrane voltage recorded; this stimulus current evoked periodic‐like oscillations in membrane voltage ...
Elisabetta Coppi   +9 more
wiley   +1 more source

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

open access: yesAdvanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

Multifunctional Manganese Oxide Nanocomposite Hydrogel With Synergistic Reactive Oxygen Species‐Scavenging, Oxygen‐Generating, Immunomodulatory, and Photothermal Antimicrobial Activities for Enhanced Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
CFP/PC@MnO2 hydrogel integrates ROS scavenging, oxygen delivery, oxidative stress reduction, immunomodulation, and photothermal antibacterial properties. The incorporation of PC@MnO2 NPs endows the hydrogel with multiple functional advantages tailored to the pathological microenvironment of diabetic wounds, including efficient ROS clearance, mitigation
Zhi Xu   +9 more
wiley   +1 more source

Green and Scalable Synthesis of Efficient and Stable CsPbBr3 Perovskite Quantum Dots Enables Low‐Threshold Amplified Spontaneous Emission

open access: yesAdvanced Science, EarlyView.
Green and scalable synthesis of CsPbBr3 perovskite quantum dots using bio‐sourced lecithin and hexane enables single‐batch production over 10 grams. Suppressed Auger recombination and electron‐phonon coupling yields 95% PLQY, enhanced stability, and low ASE thresholds of 230.4 (ns) and 50.1 (fs) µJ cm−2 in neat films. ABSTRACT Halide perovskite quantum
Yongfeng Liu   +10 more
wiley   +1 more source

Intrinsic neuronal diversity as a substrate for cortical area specialization in primate vision. [PDF]

open access: yesNat Commun
Feyerabend M   +20 more
europepmc   +1 more source

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

open access: yesAdvanced Science, EarlyView.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu   +12 more
wiley   +1 more source

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