Results 151 to 160 of about 52,697 (314)
Advanced Science, EarlyView.Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng +8 more
wiley +1 more source
Cloud Bursting and Cube Processing
, 2019 Build and configure cloud bursting ...
Jones, Ronald C.
core +1 more source
Advanced Science, EarlyView.ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang +12 more
wiley +1 more source
Orkney’s shipwreck graveyard is bursting with life [PDF]
, 2018 First paragraph: Across the North Atlantic, shipwrecks scatter the seabed like the carcasses of prehistoric creatures. Bygone relics of sea exploration, trade, migration and conflict, these historical monuments are important sites of cultural interest ...
Porter, Joanne +2 more
core
Prior Expectations Bias Confidence Judgments Through Parietal Alpha‐Band Modulation
Advanced Science, EarlyView.ABSTRACT Humans possess the metacognitive ability to estimate the likely accuracy of their own decisions through confidence judgments. Yet, whether prior information shapes confidence and the neural mechanisms mediating such influence, remain to be determined.
Luca Tarasi +4 more
wiley +1 more source
Design of monitoring and control system for water bursting in floor of coal seam
Gong-kuang zidonghua, 2013 In order to solve problems of existing water bursting prevention methods such as large difference between theoretical parameters and actual environmental parameters, poor advanced forecast and real-time performance and so on, the paper proposed a design ...
LI Cai-ping +2 more
doaj
Advanced Science, EarlyView.This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi +3 more
wiley +1 more source
, 1910 Stereoview illustrating a soldier in the foreground trying to escape from a shell bursting in the air behind ...
Unknown
core
Advanced Science, EarlyView.When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley +1 more source