Results 81 to 90 of about 52,697 (314)

Optogenetic stimulation effectively enhances intrinsically generated network synchrony

Frontiers in Neural Circuits, 2013
Synchronized bursting is found in many brain areas and has also been implicated in the pathophysiology of neuropsychiatric disorders such as epilepsy, Parkinson’s disease and schizophrenia.
Ahmed eEl Hady, Ahmed eEl Hady, Ahmed eEl Hady, Ahmed eEl Hady, Ghazaleh eAfshar, Ghazaleh eAfshar, Kai eBroeking, Kai eBroeking, Kai eBroeking, Oliver eSchlüter, Oliver eSchlüter, Oliver eSchlüter, Theo eGeisel, Theo eGeisel, Theo eGeisel, Theo eGeisel, Walter eStühmer, Walter eStühmer, Walter eStühmer, Walter eStühmer, Fred eWolf, Fred eWolf, Fred eWolf, Fred eWolf, Fred eWolf   +24 more
doaj   +1 more source

Sustainable Electrochemical Synthesis of High‐Quality MXenes: Mechanistic Insights, Applications, Challenges, and Technological Prospects

Advanced Functional Materials, EarlyView.
Electrochemical etching provides an eco‐friendly alternative to hazardous HF methods for MXene production. This approach facilitates the selective isolation of the A‐layer from MAX phases with tunable surface terminations. Controlling voltage, electrolytes, temperature, and duration enables the optimal structural integrity. Nevertheless, existing scale
Jagdeep Singh, Madhusudhana M Devadiga, Santosh K. Tiwari, AS Dhaliwal, Gurpreet Singh Selopal   +4 more
wiley   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Bursting gamma oscillations in neural mass models

Frontiers in Computational Neuroscience
Gamma oscillations (30–120 Hz) in the brain are not periodic cycles, but they typically appear in short-time windows, often called oscillatory bursts.
Manoj Kumar Nandi, Manoj Kumar Nandi, Michele Valla, Michele Valla, Matteo di Volo, Matteo di Volo   +5 more
doaj   +1 more source

Neural mechanisms underlying the generation of the lobster gastric mill motor pattern

Frontiers in Neural Circuits, 2009
The lobster gastric mill CPG is located in the stomatogastric ganglion and consists of eleven neurons whose circuitry is well known. Because all of the neurons are identifiable and accessible, it can serve as a prime experimental model for analyzing how
Allen Selverston, Attila Szücs, Attila Szücs, Ramon Huerta, Reynaldo D Pinto, Marcelo B Reyes   +5 more
doaj   +1 more source

Transcriptional Bursting and Co-Bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility

, 2019
Genes are transcribed in a discontinuous pattern referred to as RNA bursting, but the mechanisms regulating this process are unclear. Although many physiological signals, including glucocorticoid hormones, are pulsatile, the effects of transient ...
Ferguson, Matthew L., Huynh, Anh
core   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

Firing behavior and network activity of single neurons in human epileptic hypothalamic hamartoma

Frontiers in Neurology, 2013
Objective: Human hypothalamic hamartomas (HH) are intrinsically epileptogenic and are associated with treatment-resistant gelastic seizures. The basic cellular mechanisms responsible for seizure onset within HH are unknown.
Peter N. Steinmetz, Scott D. Wait, Gregory P. Lekovic, Harold L. Rekate, John F. Kerrigan   +4 more
doaj   +1 more source

The bursting fraction against total BK conductance.

, 2020
In the deterministic model (dashed curve), the bursting fraction (BF) shows a sharp jump from pure spiking (BF = 0) to pure bursting (BF = 1) at a critical value of gBK. However, with channel noise (solid curve), this step function is smoothed out and no
Joel Tabak (5659588), Jamie J. Walker (8677407), David M. Richards (8495130)   +2 more
core   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source