Results 71 to 80 of about 314,552 (258)

Cost Consequence-Based Reliability Analysis of Bursting Failure Mode in Subsea Pipelines

open access: yesنشریه مهندسی دریا, 2019
Pipelines are widely used in transporting large quantities of oil and gas productions over long distances due to their efficiency, safety and low cost.
Bahram Mehrafrooz   +2 more
doaj  

Transcriptional Bursting in Gene Expression: Analytical Results for General Stochastic Models [PDF]

open access: yesPLoS Comput. Biol., 2014
Gene expression in individual cells is highly variable and sporadic, often resulting in the synthesis of mRNAs and proteins in bursts. Such bursting has important consequences for cell-fate decisions in diverse processes ranging from HIV-1 viral ...
Niraj Kumar, Abhyudai Singh, R. Kulkarni
semanticscholar   +1 more source

Bursting in human -cell.

open access: yes, 2014
A: Experimental recording of rapid bursting in a human -cell. B: Simulation of bursting driven by via SK-channels. Default parameters except nS/pF, nS/pF, mV.
Morten Gram Pedersen (505334)   +2 more
core   +1 more source

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han   +5 more
wiley   +1 more source

Emerging Post‐CMOS Hardware Neurons for Brain‐Inspired Computing: Devices, Circuits, and System Integration

open access: yesAdvanced Functional Materials, EarlyView.
The physical realization of artificial neurons is a critical challenge for energy‐efficient neuromorphic computing. This review presents a comprehensive analysis of the evolution of artificial neuron implementations from conventional CMOS to emerging post‐CMOS technologies.
Kannan Udaya Mohanan   +4 more
wiley   +1 more source

Feed-Forward Propagation of Temporal and Rate Information Between Cortical Populations During Coherent Activation in Engineered In Vitro Networks

open access: yesFrontiers in Neural Circuits, 2016
Transient propagation of information across neuronal assembles is thought to underlie many cognitive processes. However, the nature of the neural code that is embedded within these transmissions remains uncertain.
Thomas Bryan DeMarse   +6 more
doaj   +1 more source

Exact distributions for stochastic gene expression models with bursting and feedback. [PDF]

open access: yesPhysical Review Letters, 2014
Stochasticity in gene expression can give rise to fluctuations in protein levels and lead to phenotypic variation across a population of genetically identical cells.
Niraj Kumar, T. Platini, R. Kulkarni
semanticscholar   +1 more source

An Integrated Oxygen‐Supplying Device and Predictive Multiphysics Model for Extended Ambient Transport of Insulin‐Producing Cells

open access: yesAdvanced Functional Materials, EarlyView.
Cell therapies typically rely on cold‐chain logistics and cryopreservation, limiting access and compromising cell quality. Here, a dual‐chamber device separates an oxygen‐supplying chamber from a hyaluronic acid cargo chamber, sustaining oxygen delivery for over 70 h and enabling ambient‐temperature shipment.
Daniel A. Domingo‐Lopez   +9 more
wiley   +1 more source

Response of Electrical Activity in an Improved Neuron Model under Electromagnetic Radiation and Noise

open access: yesFrontiers in Computational Neuroscience, 2017
Electrical activities are ubiquitous neuronal bioelectric phenomena, which have many different modes to encode the expression of biological information, and constitute the whole process of signal propagation between neurons.
Feibiao Zhan, Shenquan Liu
doaj   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou   +6 more
wiley   +1 more source

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