Results 31 to 40 of about 37,656 (267)
RNA Polymerase II cluster dynamics predict mRNA output in living cells
eLife, 2016 Protein clustering is a hallmark of genome regulation in mammalian cells. However, the dynamic molecular processes involved make it difficult to correlate clustering with functional consequences in vivo. We developed a live-cell super-resolution approach
Won-Ki Cho +10 more
doaj +1 more source
NbO2 Memristive Neurons for Burst‐Based Perceptron
Advanced Intelligent Systems, 2020 Neuromorphic computing using spike‐based learning has broad prospects in reducing computing power. Memristive neurons composed with two locally active memristors have been used to mimic the dynamical behaviors of biological neurons.
Yeheng Bo +5 more
doaj +1 more source
Burst-by-burst adaptive joint detection CDMA [PDF]
1999 IEEE 49th Vehicular Technology Conference (Cat. No.99CH36363), 2003 Adaptive quadrature amplitude modulation (AQAM) is combined with joint detection code division multiple access (JD-CDMA) in order to increase the throughput of a communications system, while maintaining a target BER. The QAM modes are adaptively switched, by estimating the signal to interference plus noise ratio (SINR) at the output of the joint ...
Kuan, E.L., Wong, C.H., Hanzo, L.
openaire +1 more source
Multiple mechanisms of bursting in a conditional bursting neuron [PDF]
The Journal of Neuroscience, 1987 The anterior burster (AB) neuron in the stomatogastric ganglion of the spiny lobster, Panulirus interruptus, is a conditional burster in the pyloric motor circuit. Bath application of the monoamines dopamine, serotonin, and octopamine induces rhythmic bursting pacemaker potentials in a silent, synaptically isolated AB cell. However, each amine produces
R M, Harris-Warrick, R E, Flamm
openaire +2 more sources
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Frontiers in Computational Neuroscience, 2013 Upon sensory stimulation, primary cortical areas readily engage in narrow-band rhythmic activity between 30 to 90 Hz, the so-called gamma oscillations.
Belén eDe Sancristóbal +5 more
doaj +1 more source
Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer +11 more
wiley +1 more source