Results 81 to 90 of about 59,148 (256)
Advanced Healthcare Materials, EarlyView.Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao +10 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li +9 more
wiley +1 more source
Complex oscillations in an electrically stimulated membrane model
Journal of the Brazilian Chemical Society, 1999 Este artigo investiga, teoricamente, a dinâmica de um modelo de membrana sob estimulação elétrica externa. Este sistema mostra vários tipos de respostas oscilatórias no potencial da membrana, quando uma corrente sinoidal AC é superposta à corrente DC ...
Delgado E.J., Münster A.F.
doaj
Advanced Healthcare Materials, EarlyView.NeuroVisio SyncPatch integrates skin‐conformal electromyography (EMG) electrodes with camera‐tracked markers to jointly assess muscle activity and three‐dimensional knee kinematics during rehabilitation. Parallel feedback pathways provide real‐time kinematic guidance during movement and post‐trial neuromuscular feedback.
Bohyung Choi +11 more
wiley +1 more source
Multiple mechanisms of bursting in a conditional bursting neuron
, 1987 The anterior burster (AB) neuron in the stomatogastric ganglion of the spiny lobster, Panulirus interruptus, is a conditional burster in the pyloric motor circuit.
RM Harris-Warrick, RE Flamm
core +1 more source
Estrogen‐dependent control and cell‐to‐cell variability of transcriptional bursting
Molecular Systems Biology, 2018 Cellular decision‐making and environmental adaptation are dependent upon a heterogeneous response of gene expression to external cues. Heterogeneity arises in transcription from random switching between transcriptionally active and inactive states ...
Christoph Fritzsch +5 more
doaj +1 more source
Emergent bursting and synchrony in computer simulations of neuronal cultures
Frontiers in Computational Neuroscience, 2012 Experimental studies of neuronal cultures have revealed a wide variety of spiking network activity ranging from sparse, asynchronous firing to distinct, network-wide synchronous bursting.
Niru eMaheswaranathan +3 more
doaj +1 more source
Stretchable Microelectrode Arrays for Electro‐Mechanical Probing of Brain Spheroids
Advanced Healthcare Materials, EarlyView.A multimodal device featuring kirigami‐patterned stretchable microelectrode arrays enables concurrent mechanical actuation and electrophysiological recording of brain spheroids. The platform supports multiple loading regimes and reveals mechanically induced modulation of spontaneous network activity in 3D neural tissue models.
Eleonora Martinelli +17 more
wiley +1 more source
Modeling neuronal bursting: singularity theory meets neurophysiology [PDF]
, 2013 Exploiting the speci c structure of neuron conductance-based models, the paper investigates the mathematical modeling of neuronal bursting. The proposed approach combines singularity theory and geometric singular perturbations to unfold the geometry of ...
Franci, Alessio +2 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar +6 more
wiley +1 more source