Results 41 to 50 of about 60,335 (260)
Noise-tuned bursting in a Hedgehog burster
Frontiers in Computational Neuroscience, 2022 Noise can shape the firing behaviors of neurons. Here, we show that noise acting on the fast variable of the Hedgehog burster can tune the spike counts of bursts via the self-induced stochastic resonance (SISR) phenomenon.
Jinjie Zhu, Jinjie Zhu, Hiroya Nakao
doaj +1 more source
RNA Polymerase II cluster dynamics predict mRNA output in living cells
eLife, 2016 Protein clustering is a hallmark of genome regulation in mammalian cells. However, the dynamic molecular processes involved make it difficult to correlate clustering with functional consequences in vivo. We developed a live-cell super-resolution approach
Won-Ki Cho +10 more
doaj +1 more source
NbO2 Memristive Neurons for Burst‐Based Perceptron
Advanced Intelligent Systems, 2020 Neuromorphic computing using spike‐based learning has broad prospects in reducing computing power. Memristive neurons composed with two locally active memristors have been used to mimic the dynamical behaviors of biological neurons.
Yeheng Bo +5 more
doaj +1 more source
Simple models of bursting and non-bursting P-type electroreceptors [PDF]
, 2001 Weakly electric "sh use phase and amplitude modulations of their electric organ discharge to communicate and to capture prey (electrolocation).
Andreh Longtin +3 more
core +1 more source
Modeling neuronal bursting: singularity theory meets neurophysiology [PDF]
, 2013 Exploiting the speci c structure of neuron conductance-based models, the paper investigates the mathematical modeling of neuronal bursting. The proposed approach combines singularity theory and geometric singular perturbations to unfold the geometry of ...
Franci, Alessio +2 more
core +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
FEBS Open Bio, EarlyView.Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Frontiers in Computational Neuroscience, 2013 Upon sensory stimulation, primary cortical areas readily engage in narrow-band rhythmic activity between 30 to 90 Hz, the so-called gamma oscillations.
Belén eDe Sancristóbal +5 more
doaj +1 more source
, 2018 Data from toxin and antitoxin bursting simulations used in Figure ...
Arnab Bandyopadhyay (5675015) +1 more
core +1 more source