Results 51 to 60 of about 228,030 (265)

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin   +13 more
wiley   +1 more source

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao   +8 more
wiley   +1 more source

TOWARDS A BUSINESS MODELS CLASSIFICATION [PDF]

open access: yesAnnals of the University of Oradea: Economic Science
In the contemporary environment, companies are configured not only as traditional economic actors, but as veritable nodes of intermediation of ideas and creations, capable of articulating new forms of value and competitiveness in a context marked by ...
Olimpia BAN, Xhorxhina VANGJEL
doaj   +1 more source

The Chain Reactions of Business Models and Strategies [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2021
When researching business models in the available literature, the concept of strategy comes up frequently. It is typically portrayed that these two concepts are intertwined and must be used in tandem to achieve a company's goals and objectives.
Gabriela Andrisan, Andra Modreanu
doaj  

Phase‐Resolved Dual Control of Phenol Photodissociation at the Air–Water Interface From Structure‐Resolved Statistics

open access: yesAdvanced Science, EarlyView.
Faster phenol photolysis at the air–water interface arises from two cooperative factors: a more favorable initial microenvironment for solvent‐side electron stabilization, which lowers CI access, and a more labile hydrogen‐bond network, which more readily reorganizes to stabilize the dark‐state intermediate.
Qiang Yin   +8 more
wiley   +1 more source

Open Hardware Business Models [PDF]

open access: yesTechnology Innovation Management Review, 2008
In the September issue of the Open Source Business Resource, Patrick McNamara, president of the Open Hardware Foundation, gave a comprehensive introduction to the concept of open hardware, including some insights about the potential benefits for both ...
Edy Ferreira
doaj  

Vacancy‐Driven Ni Exsolution in Prussian Blue Analogues Creates Cooperative Defect–Metal Sites for Alkaline Hydrogen Evolution

open access: yesAdvanced Science, EarlyView.
Multimetal Prussian blue analogues (PBAs) are converted by low‐temperature Ar annealing into a cavity/CN‐vacancy architecture that triggers in situ Ni exsolution, creating dense Ni‐PBA interfacial motifs. These motifs optimize water dissociation and H* adsorption in alkaline media, delivering markedly accelerated HER kinetics and long‐term stability ...
Shiqi Wang   +5 more
wiley   +1 more source

BUSINESS MODELS FOR ONLINE EDUCATION

open access: yesOnline Learning, 2019
Nine institutions—Colorado State University, Dallas County Community College District (DCCCD), Duquesne University, Georgia Institute of Technology, University of Central Florida, The University of Illinois at Springfield, University of Massachusetts ...
George Lorenzo
doaj   +1 more source

Surface‐Spin‐Induced Magnetic Loss Enhancement in Ultralight Electromagnetic Absorbers

open access: yesAdvanced Science, EarlyView.
Fe3O4 nanoparticles with different hollow rates were synthesized to demonstrate the key role of surface moment in magnetic loss process. Using the same volume filling ratio, the 54.1% hollow Fe3O4 absorber represents about 20% enhancement in the imaginary part (μ'') than solid particles due to the coexisting magnetic resonance of inside and outside ...
Ruimin Ren   +5 more
wiley   +1 more source

Toward Smart City Business Models

open access: yesJournal of Business Models, 2018
This paper discusses a business model concept in a public smart city context. To date, there is no unified understanding of how smart cities create value for their stakeholders.
Sari Perätalo, Petri Ahokangas
doaj   +1 more source

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