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Novel genomic targets for proper subtyping of bovine viral diarrhea virus 1 (BVDV-1) and BVDV-2

Virus Genes, 2023
Whole-genome phylogenetic analysis, the most suitable strategy for subtyping bovine viral diarrhea virus 1 (BVDV-1) and BVDV-2, is not feasible for many laboratories. Consequently, BVDV isolates/strains have been frequently subtyped based on analysis of single genomic regions, mainly the 5' untranslated region (UTR). This approach, however, may lead to
Carolina Isabela Mucellini   +4 more
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Verlauf einer Herdeninfektion mit BVDV-2

Tierärztliche Praxis Ausgabe G: Großtiere / Nutztiere, 2005
Zusammenfassung Gegenstand und Ziel: In der Fallstudie werden die klinischen Erkrankungen einer schweren akuten BVDV-2-Infektion mit hohen wirtschaftlichen Verlusten in einer Milchviehherde beschrieben und der Infektionsverlauf labordiagnostisch nachvollzogen.
R. Mansfeld, Sabine Kühne, R. Martin
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Occurrence of a second strain of bvdv‐2 in the uk

Veterinary Record, 2007
SIR, — We wish to draw attention to the occurrence of a second strain of bovine viral diarrhoea virus type 2 (bvdv-2) in the uk. This strain was detected and isolated as a consequence of clinical investigations carried out by the Veterinary Laboratories Agency (vla) in cooperation with ...
Trevor, Drew   +2 more
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Pig BVDV-2 non-structural protein (Npro) links to cellular antiviral response in vitro

Virus Genes, 2016
In this study, we constructed for the first time a full-length cDNA clone of pig-original bovine viral diarrhea virus 2 (BVDV-2) strain SH-28, modified the cDNA clone (pASH28) for mutant pASHΔNpro and derived virus strain vASHΔNpro by deleting the genomic region encoding the Npro polypeptide, and examined significance of protein Npro for antiviral ...
Jie, Tao   +8 more
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Border disease‐like clinical signs in sheep caused by a BVDV‐2 type d

Veterinary Record Case Reports, 2017
The present paper accounts for the study of an outbreak of abortions within a sheep herd over a span of three months. To this purpose, one of the aborted fetuses that tested positive for bovine viral diarrhoea virus (BVDV), specifically BVDV‐2, was analysed by RT‐qPCR. Afterwards, sera from all the animals in the herd were collected in order to perform
Maria Carmen Eiras   +4 more
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Investigation of a dual fetal infection model with bovine viral diarrhoea viruses (BVDV)-1 and BVDV-2

Archives of Virology, 2011
Two studies were performed in pregnant heifers to determine whether inoculation with two bovine viral diarrhoea viruses (BVDV), one BVDV-1 and one BVDV-2, inoculated separately into either nostril, results in fetal infection with both viruses.
B, Makoschey, M G J, Janssen
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Pathogenetic differences after experimental infection of calves with Korean non-cytopathic BVDV-1 and BVDV-2 isolates

Veterinary Immunology and Immunopathology, 2013
The purpose of this study was to compare clinical and virological differences between non-cytopathic (ncp) bovine viral diarrhea virus (BVDV)-1 and ncp BVDV-2 isolated from Korean field cases. Each five naïve calves were experimentally infected with Korean ncp BVDV-1 or BVDV-2 isolates.
Giyong, Seong   +2 more
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Efficacy of a combination modified-live IBR-BVD-PI3-BRSV vaccine + Mannheimia haemolytica toxoid against challenge with virulent BVDV-1b and BVDV-2 viruses in young calves 60 days of age

The Bovine Practitioner, 2021
Efficacy of attenuated (att) bovine viral diarrhea virus (types 1 and 2) as antigen fractions in a modified-live multivalent vaccine were evaluated following single, subcutaneous (SC) administration and intranasal (IN) challenge 35 to 38 d after vaccination, with either virulent BVDV-1b (Study 1) or BVDV-2 (Study 2) viruses in young calves.
Masic, Aleksandar   +10 more
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Experimental Infection of Calves with Bovine Viral Diarrhoea Virus Type-2 (BVDV-2) Isolated from a Contaminated Vaccine

Veterinary Research Communications, 2003
A non-cytopathic strain of BVDV-2 was isolated from a batch of live infectious bovine rhinotracheitis (IBR) vaccine, and inoculated intranasally into four 3-month-old calves. Severe signs of disease developed by days 4 and 6 in three of the calves, free of BVDV and antibodies to BVDV, that had been exposed to the virus.
E, Falcone   +9 more
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Experimental infection of pregnant ewes with bovine viral diarrhea virus type-2 (BVDV-2): effects on the pregnancy and fetus

Veterinary Microbiology, 2001
The reproduction effects of bovine viral diarrhea virus type-2 (BVDV-2) infection were investigated in ewes inoculated with a non-cytopathic BVDV-2 isolate at three stages of gestation. Virus inoculation was followed by a transient viremia, accompanied by a transient and mild hyperthermia and nasal discharge in a few animals.
C F, Scherer   +6 more
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