Results 51 to 60 of about 10,021 (175)

Priming Cross-Protective Bovine Viral Diarrhea Virus-Specific Immunity Using Live-Vectored Mosaic Antigens. [PDF]

PLoS ONE, 2017
Bovine viral diarrhea virus (BVDV) plays a key role in bovine respiratory disease complex, which can lead to pneumonia, diarrhea and death of calves. Current vaccines are not very effective due, in part, to immunosuppressive traits and failure to induce ...
Shehnaz Lokhandwala, Xin Fang, Suryakant D Waghela, Jocelyn Bray, Leo M Njongmeta, Andy Herring, Karim W Abdelsalam, Christopher Chase, Waithaka Mwangi   +8 more
doaj   +1 more source

Design Space Assessment of Virus Inactivation in Plasma‐Derived Matrices Establishes a Single Detergent Alternative to TX‐100‐Containing Mixes

Biotechnology and Bioengineering, Volume 123, Issue 7, Page 1967-1975, July 2026.
ABSTRACT The detergent Triton X‐100 (TX‐100) is a typical component of solvent/detergent (S/D) mixes applied for virus inactivation steps of biomanufacturing processes, yet environmentally unfavorable properties have led to restrictions on its use. Deviron 13‐S9 has recently been described as an eco‐friendly TX‐100 alternative, with powerful virus ...
Johanna Kindermann, Cecilie Klausen, Michael Karbiener, Thomas R. Kreil   +3 more
wiley   +1 more source

Mosaic BVDV vaccine induced BVDV-1 specific neutralizing antibodies.

, 2017
Serum neutralization assays were used to evaluate BVDV-1-specific neutralization titers at A) One-week post-boost; and B) one-week pre-challenge against five BVDV type 1 strains. Mean group titers are represented by the bars.
Jocelyn Bray (3666634), Waithaka Mwangi (393312), Suryakant D. Waghela (3666643), Andy Herring (3666631), Karim W. Abdelsalam (3666640), Christopher Chase (3666646), Shehnaz Lokhandwala (3666637), Xin Fang (134979), Leo M. Njongmeta (369400)   +8 more
core   +1 more source

Anti-BVDV Activity of Traditional Chinese Medicine Monomers Targeting NS5B (RNA-Dependent RNA Polymerase) In Vitro and In Vivo

Molecules, 2023
Natural products have emerged as “rising stars” for treating viral diseases and useful chemical scaffolds for developing effective therapeutic agents.
Nannan Chen, Dongjun Jiang, Baihui Shao, Tongtong Bai, Jinwei Chen, Yu Liu, Zecai Zhang, Yulong Zhou, Xue Wang, Zhanbo Zhu   +9 more
doaj   +1 more source

BVDV antigen expression constructs.

, 2017
A) Schematic diagram of expression cassettes encoding BVDV mosaic antigens: i) Composition of the nproe21-3, chimeric gene: npro encodes Npro antigen; e21 encodes a mosaic BVDV-1a E2 envelope glycoprotein; e22 encodes a mosaic BVDV-1b E2 envelope ...
Jocelyn Bray (3666634), Waithaka Mwangi (393312), Suryakant D. Waghela (3666643), Andy Herring (3666631), Karim W. Abdelsalam (3666640), Christopher Chase (3666646), Shehnaz Lokhandwala (3666637), Xin Fang (134979), Leo M. Njongmeta (369400)   +8 more
core   +1 more source

Mosaic BVDV vaccine induced BVDV-2 specific neutralizing antibodies.

, 2017
BVDV-2-specific neutralization titers against three BVDV type 2 strains were evaluated at A) two weeks post-boost; and B) one week pre-challenge. Mean group titers are represented by the bars.
Jocelyn Bray (3666634), Waithaka Mwangi (393312), Suryakant D. Waghela (3666643), Andy Herring (3666631), Karim W. Abdelsalam (3666640), Christopher Chase (3666646), Shehnaz Lokhandwala (3666637), Xin Fang (134979), Leo M. Njongmeta (369400)   +8 more
core   +1 more source

Diversidade antigênica de amostras do vírus da diarréia viral bovina isoladas no Brasil: implicações para o diagnóstico e estratégias de imunização

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2000
Seqüenciamento e análise filogenética de 17 amostras do vírus da diarréia viral bovina (BVDV) isoladas no Brasil identificaram quatro amostras (23,5%) do genótipo 1a (BVDV-1a), nove amostras (52,9%) do genótipo 1b (BVDV tipo 1b) e quatro amostras (23,5%)
E.F. Flores, R. Weiblen, L.H.V.G. Gil, F.L. Tobias, M. Lima, D.C. Garcez, S.A. Botton   +6 more
doaj   +1 more source

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, Volume 13, Issue 32, 9 June 2026.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source

Immunohistochemical diagnosis of persistent infection with Bovine Viral Diarrhea Virus (BVDV) on skin biopsies

, 2007
Detection of persistent infection with BovineViral Diarrhea Virus (BVDV) is essential for both epidemiological and clinical reasons. In addition to the classical virological methods such as virus isolation in tissue culture, ELISA and RT-PCR ...
Ehrensperger, F, Braun, Ueli; https://orcid.org/, Zlinszky, K, Hilbe, M, Braun, U, Hilbe, Monika, Peterhans, E, Schaller, P, Arquint, A   +8 more
core   +1 more source

BVDV permissiveness and lack of expression of co-stimulatory molecules on PBMCs from calves pre-infected with BVDV [PDF]

, 2020
Bovine viral diarrhea virus (BVDV) has been detected in peripheral blood mononuclear cells (PBMCs) of immunocompetent animals, not being clear whether the development of a specific humoral immune response can prevent BVDV infection. The aim of this study
Risalde, M.A., Romero-Palomo, F., Gómez-Villamandos, J.C., Besozzi, Martina, Ceciliani, Fabrizio, Comazzi, Stefano, Romero-Palomo, Fernando, Luzzago, C., Lecchi, Cristina, Lecchia, Cristina, Comazzia, Stefano, Luzzago, Camilla, Risalde, María A., Bazzocchi, Chiara, Gómez-Villamandos, Jose C.   +14 more
core   +1 more source