Results 111 to 120 of about 15,437,251 (300)

Istituzioni ritmiche e fine del tempo. "Modo" e "neuma" nel canto gregoriano e in Olivier Messiaen

open access: yesDoctor Virtualis, 2011
Prendendo le mosse dall’esame del ciclo pianistico Quatre études de rythme, di Olivier Messiaen (e in particolare del terzo brano, Neumes rythmiques), scritto fra il 1949 e il 1950, l’articolo delinea un sintetico confronto fra due differenti espressioni
Marco Mazzolini
doaj   +1 more source

Towards the field binary population: Influence of orbital decay on close binaries

open access: yes, 2012
Surveys of the binary populations in the solar neighbourhood have shown that the periods of G- and M-type stars are log-normally distributed. However, observations of young binary populations suggest a log-uniform distribution.
Allison   +40 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Immanenza e trascendenza: Dal Pra, il medioevo e il problema di Dio

open access: yesDoctor Virtualis, 2008
La discussione delle grandi narrazioni storiografiche del pensiero medievale. Il definirsi di una prospettiva teorica e di una storiografica attraverso il confronto con Scoto Eriugena. La ricerca di un senso e il problema di Dio.
Alice De Fortunato, Marco Rossini
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

La valle di Giosafat e le crepe della metafisica

open access: yesDoctor Virtualis, 2008
Il trascendentalismo della prassi per andare oltre lo scetticismo e oltre ogni pretesa da parte della filosofia di cogliere l'essere nella sua definizione universale e razionale. Una proposta anche storiografica.
Chiara Selogna
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Dynamo Induced by Time-periodic Force [PDF]

open access: yesThe Astrophysical Journal Letters, 2018
Abstract To understand the dynamo driven by time-dependent flow, e.g., turbulence, we investigate numerically the dynamo induced by time-periodic force in rotating magnetohydrodynamic flow and focus on the effect of force frequency on the dynamo action. It is found that the dynamo action depends on the force frequency.
openaire   +2 more sources

Ultra-fine beryllium powder by amalgam process Progress report, period ending 31 Oct. 1966 [PDF]

open access: yes
Metallurgical evaluation of beryllium powdered metal, and electron microscope studies of agglomerate particle ...
Griffiths, V.   +4 more
core   +1 more source

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