Results 151 to 160 of about 68,973,280 (347)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Variazioni sul tema per una possibile storia del pensiero critico. Annotazioni intorno a Nicola di Autrécourt, Hume e Husserl

Doctor Virtualis
L’articolo si propone di approfondire il progetto di Mario Dal Pra per una storia del pensiero critico tratteggiato negli studi sullo scetticismo greco, sui pensatori medievali che hanno sollevato questioni critiche o scettiche (Giovanni di Salisbury e ...
Amalia Salvestrini
doaj   +1 more source

The Performance of Mutual Funds in the Period 1945-1964

, 1968
Michael C. Jensen
semanticscholar   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Incubation Period: Not well determined; may be as short as 1-3 days.

, 2014
Presumably until discharges of the mouth and nose no longer contain virulent pneumococci in significant numbers. Penicillin will render patients with susceptible strains noninfectious within 24-48 hours.
Infectious Period
core  

Anno 1300: l'attesa dei tempi nuovi. Guglielma e Dolcino da Novara

Doctor Virtualis
L’anno 1300 mostra un contesto profetico e di attesa escatologica che sollecita le indagini degli inquisitori dell’eretica pravità che intervengono contro eretiche ed eretici che mostrano un pensiero non conformista.
Marina Benedetti
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

On the relationship between period and cohort mortality [PDF]

In this paper I explore the formal relationship between period and cohort mortality, focusing on a comparison of measures of mean lifespan. I consider not only the usual measures (life expectancy at birth for time periods and birth cohorts) but also some
John R. Wilmoth
core  

Age-period-cohort model for MMR.

, 2018
Age-period-cohort model for MMR.
Román Rodríguez-Aguilar (4990160)
core   +1 more source

Non contra sed supra: l’ordine delle leggi nel pensiero di Bonaventura da Bagnoregio

Doctor Virtualis
L’articolo si propone di formulare una prima ipotesi relativa ai rapporti fra i diversi tipi di legge presenti nel pensiero di Bonaventura da Bagnoregio; la ricostruzione avverrà a partire dal basso, prendendo le mosse dalla lex politica, per risalire ...
Marco Rossini
doaj   +1 more source