Results 51 to 60 of about 532,911 (247)

Selection of the Optimal Femoropopliteal Bypass Strategy According to Autologous Vein Availability and Graft Thrombosis Risk

Инновационная медицина Кубани
Background: Femoropopliteal bypass remains a priority surgical method for treating extensive atherosclerosis of the lower limb arteries. Selecting the optimal intervention strategy is challenging even for experienced vascular surgeons, which highlights ...
A. B. Zakeryaev, R. A. Vinogradov, T. E. Bakhishev, S. R. Butaev, G. A. Khangereev, A. G. Baryshev, V. A. Porhanov   +6 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Flash Gas Bypass Method for Improving Performance of an A/C System With a Microchannel Evaporator [PDF]

, 2012
This paper demonstrates that Flash Gas Bypass (FGB) method significantly improved the performances of the microchannel evaporator and the system, compared to the conventional direct expansion (DX) system.
Hrnjak, Predrag S., Tuo, Hanfei
core   +1 more source

A novel, reusable, realistic neurosurgical training simulator for cerebrovascular bypass surgery: Iatrotek® bypass simulator validation study and literature review

Frontiers in Surgery, 2023
BackgroundMicroanastomosis is a challenging technique requiring continuous training to be mastered. Several models have been proposed, but few effectively reflect a real bypass surgery; even fewer are reusable, most are not easily accessible, and the ...
Marcello D’Andrea, Antonio Musio, Roberto Colasanti, Lorenzo Mongardi, Dalila Fuschillo, Giorgio Lofrese, Luigino Tosatto   +6 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Inhibition of neutrophil activity improves cardiac function after cardiopulmonary bypass [PDF]

, 2007
Background The arterial in line application of the leukocyte inhibition module (LIM) in the cardiopulmonary bypass (CPB) limits overshooting leukocyte activity during cardiac surgery.
Windolf Joachim, Scholz Martin, Francischetti, Ieda, Kranert Tilmann, Bitu-Moreno José, Moritz Anton, Francischetti Ieda, Kranert, Tilmann, Windolf, Joachim, Lögters, Tim Tobias, Bitu-Moreno, José, Margraf, Stefan, Abdel-Rahman Ulf, Abdel-Rahman, Ulf, Aybek, Tayfun, Grünwald, Frank (Prof. Dr.), Lögters Tim, Margraf Stefan, Grünwald Frank, Scholz, Martin, Moritz, Anton, Aybek Tayfun   +21 more
core   +1 more source

3D Exoscopes in Experimental Microanastomosis: A Comparison of Different Systems

Life, 2023
Background: In recent years, three-dimensional exoscopes have been increasingly applied in neurosurgery. Multiple exoscopic systems are available, all offering specific features.
Ahmad Hafez, Roel Haeren, Justiina Huhtakangas, Ville Nurminen, Mika Niemelä, Martin Lehecka   +5 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Episode of coexisting infections with multiple dengue virus serotypes in central Karnataka, India

Journal of Infection and Public Health, 2013
Summary: Background: The co-circulation of multiple dengue virus serotypes has been reported in many parts of the world, including India; however, concurrent infection with more than one serotype of dengue virus in the same individual is rarely ...
C.S. VinodKumar, N.K. Kalapannavar, K.G. Basavarajappa, D. Sanjay, Chandrasekar Gowli, Naveen G. Nadig, B.S. Prasad   +6 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source