Results 61 to 70 of about 1,015,635 (341)

Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior

Advanced Healthcare Materials, EarlyView.
Fibrous structures are key elements of the native extracellular matrix and crucial for directing cell behavior. This review discusses how fiber properties such as composition, diameter, and alignment affect cell responses in 2D and 3D systems. Strategies for integrating fibrous cues into engineered tissues are highlighted, and future directions for ...
Zan Lamberger, Gregor Lang
wiley   +1 more source

Programmable Compliance in Small‐Diameter Vascular Grafts by Design of Melt‐Electrowritten Scaffold Architectures for In Situ Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Small‐diameter vascular grafts with compliance tunable by design are fabricated via melt electrowriting. By controlling the winding angle of intertwined helical fibers, grafts with compliances matching those of human vessels, from veins to arteries, are realized. This holds the potential of avoiding a compliance mismatch, which has been identified as a
Kilian Maria Arthur Mueller, Christina Ahrens, Linda Grefen, Salma Mansi, Dario Arcuti, Elena De‐Juan‐Pardo, Felix Kur, Christian Hagl, Petra Mela   +8 more
wiley   +1 more source

Effect of concurrent mitral valve surgery for secondary mitral regurgitation upon mortality after aortic valve replacement or coronary artery bypass surgery

Frontiers in Cardiovascular Medicine, 2023
ObjectivesIt is uncertain whether concurrent mitral valve repair or replacement for moderate or greater secondary mitral regurgitation at the time of coronary artery bypass graft or aortic valve replacement surgery improves long-term survival ...
Shyamal R. Asher, Chin Siang Ong, Raymond J. Malapero, Mahyar Heydarpour, Gregory W. Malzberg, Jasmine T. Shahram, Thy B. Nguyen, Douglas C. Shook, Stanton K. Shernan, Prem Shekar, Tsuyoshi Kaneko, Rodolfo Citro, Jochen D. Muehlschlegel, Simon C. Body   +13 more
doaj   +1 more source

Uniting 4D Printing and Melt Electrowriting for the Enhancement of Regenerative Small Diameter Vascular Grafts

Advanced Healthcare Materials, EarlyView.
A hybrid 4D printing strategy enables the fabrication of shape‐morphing, mechanically reinforced tubular constructs for vascular tissue engineering. By combining alginate‐methylcellulose hydrogels with melt electrowritten polycaprolactone fibers and protein‐based functionalization, this platform supports spatially organized co‐cultures of fibroblasts ...
Max von Witzleben, Akvilė Gasiūnaitė, Marlene Ihle, Ashwini Rahul Akkineni, Kathleen Schütz, Tilman Ahlfeld, Michael Gelinsky, Anja Lode, Sarah Duin   +8 more
wiley   +1 more source

Predictive Values of Systemic Immune-Inflammation Index in New-Onset Atrial Fibrillation Following Coronary Artery Bypass Grafting

Brazilian Journal of Cardiovascular Surgery, 2022
Introduction: We investigated the relationship between the newly-defined systemic immune-inflammation index and the new-onset atrial fibrillation in patients undergoing coronary artery bypass grafting.
Yucel Yilmaz, Saban Kelesoglu, Deniz Elcik, Rifat Ozmen, Nihat Kalay   +4 more
doaj   +1 more source

European Multicenter Study on Coronary Artery Bypass Grafting (E-CABG registry): Study Protocol for a Prospective Clinical Registry and Proposal of Classification of Postoperative Complications

Journal of Cardiothoracic Surgery, 2015
BackgroundClinical evidence in coronary surgery is usually derived from retrospective, single institutional series. This may introduce significant biases in the analysis of critical issues in the treatment of these patients.
F. Biancari, V. Ruggieri, A. Perrotti, P. Svenarud, M. Dalén, F. Onorati, G. Faggian, G. Santarpino, D. Maselli, C. Dominici, S. Nardella, F. Musumeci, R. Gherli, G. Mariscalco, N. Masala, A. Rubino, C. Mignosa, M. de Feo, A. D. Corte, C. Bancone, S. Chocron, G. Gatti, T. Gherli, E. Kinnunen, T. Juvonen   +24 more
semanticscholar   +1 more source

Cyclic Peptide–Polymer Conjugate Nanotubes for Delivery of SN‐38 in Treatment of Colorectal Cancer Model

Advanced Healthcare Materials, EarlyView.
This study develops cyclic peptidepolymer conjugate nanotubes with hydrophobic, drug‐rich cores to enhance drug loading and stability, and demonstrates their responsive disassembly, pharmacokinetics, and anti‐tumour efficacy in colorectal cancer models using the anticancer drug SN‐38.
Sophie K. Hill, Min Zeng, Santhosh Kalash Rajendrakumar, Robert Dallmann, Sébastien Perrier   +4 more
wiley   +1 more source

Perioperative management of adult patients undergoing coronary artery bypass grafting and valve surgery: a literature review [PDF]

Einstein (São Paulo)
Purpose of review Coronary artery bypass grafting, revascularization by percutaneous coronary intervention, and heart valve surgery are crucial therapeutic interventions for patients with various cardiovascular diseases. The objective of this literature
Nair Naiara Barros de Vasconcelos, Veronica Neves Fialho Queiroz, Guilherme Martins de Souza, Sandrigo Mangini, Fernando Morita Fernandes Silva, Luiz Guilherme Villares da Costa, Pedro Paulo Zanella do Amaral Campos, Samuel Padovani Steffen, Flávio Takaoka, Ary Serpa Neto, Adriano José Pereira, Carmen Silvia Valente Barbas, Thiago Domingos Corrêa, Renato Carneiro de Freitas Chaves   +13 more
doaj   +1 more source

Shedding Light on the Cellular Uptake Mechanisms of Bioactive Glass Nanoparticles as Controlled Intracellular Delivery Platforms: A Review of the Recent Literature

Advanced Healthcare Materials, EarlyView.
This review summarizes the main uptake pathways of bioactive glass nanoparticles (BGNs) and their intracellular localization, highlighting that BGNs are mainly internalized and entrapped within endosomes/lysosomes. Strategies for controlled intracellular ion release, with implications for targeted modulation of cell behavior, are discussed. The need to
Andrada‐Ioana Damian‐Buda, Aldo R. Boccaccini   +1 more
wiley   +1 more source

Impact of malnutrition on postoperative delirium development after on pump coronary artery bypass grafting

Journal of Cardiothoracic Surgery, 2015
Background & aimsEven though malnutrition is frequently observed in cardiac population outcome data after cardiac surgery in malnourished patients is very rare.
D. Ringaitiene, D. Gineitytė, V. Vicka, Tadas Žvirblis, J. Šipylaitė, A. Irnius, J. Ivaškevičius, Tomas Kacergius   +7 more
semanticscholar   +1 more source