Results 141 to 150 of about 3,051,865 (432)

In Vivo Cytosolic Delivery of Biomolecules into Neurons for Super‐Resolution Imaging and Genome Modification

Advanced Science, EarlyView.
The N1 peptide specifically targets neurons, enabling cytosolic delivery of fluorescent dyes and proteins for super‐resolution imaging and functional genetic modification. Abstract Efficient delivery of biomolecules into neurons has significant impacts on therapeutic applications in the central nervous system (CNS) and fundamental neuroscience research.
Xiaoqian Ge, Joseph B. Wekselblatt, Scott Elmore, Bo Wang, Tongtong Wang, Renjinming Dai, Tingting Zhang, Harsh Dave, Mohammadaref Ghaderi, Athul Raj Anilkumar, Bill Wang, Shashank R. Sirsi, Jung‐Mo Ahn, Mikhail G. Shapiro, Yuki Oka, Carlos Lois, Zhenpeng Qin   +16 more
wiley   +1 more source

Comparison of long-term outcome after endovascular therapy versus bypass surgery in claudication patients with Trans-Atlantic Inter-Society Consensus-II C and D femoropopliteal disease.

Circulation Journal, 2014
BACKGROUND Although endovascular therapy (EVT) has advanced, few reports have compared EVT and bypass surgery in claudication patients with femoropopliteal disease.
H. Aihara, Y. Soga, S. Mii, J. Okazaki, T. Yamaoka, D. Kamoi, Yoshiaki Shintani, Toshinobu Ishikawa   +7 more
semanticscholar   +1 more source

Bioinspired Claw‐Engaged Adhesive Microparticles Armed with γGC Alleviate Ulcerative Colitis via Targeted Suppression of Macrophage Ferroptosis

Advanced Science, EarlyView.
γGC deficiency in ulcerative colitis drives macrophage ferroptosis‐mediated inflammation. Claw‐engaged microparticles armed with γGC (γGC‐MPs) enhance lesion targeting, promoting localized γGC release and tissue uptake. On the cover, Monkey King (Macrophages) was bound by the Immortal‐Binding Rope and subsequently sealed beneath the Five‐Fingered ...
Rong Wang, Jianwei Zhu, Jinyi Zhou, Jinyang Li, Min Wang, Yuqi Wu, Danshan Zhao, Xiancheng Chen, Xiaoyuan Chen, Yuetong Wang, Jianhua Zou   +10 more
wiley   +1 more source

To Pace Or Not To Pace! – Prevention Of Atrial Fibrillation After Coronary Artery Bypass Surgery [PDF]

, 2005
Atrial fibrillation (AF) is a very undesirable, but unfortunately a common arrhythmia following coronary artery bypass graft (CABG) surgery, occurring in up to 40% of patients.
Vora, Amit
core   +2 more sources

Clinical outcomes of remote ischemic preconditioning prior to cardiac surgery: A meta‐analysis of randomized controlled trials [PDF]

, 2017
Background Multiple randomized controlled trials of remote ischemic preconditioning ( RIPC ) prior to cardiac surgery have failed to demonstrate clinical benefit. The aim of this updated
Bole, Indra, Brown, David L, Patel, Vaiibhav, Pierce, Brian   +3 more
core   +2 more sources

Drug Screening of Primary Human Endometriotic Cells Based on Micro‐Encapsulating Microfluidic Chip

Advanced Science, EarlyView.
To address the challenges of unclear mechanisms and poor therapeutic efficacy in endometriosis (EMs), this study develops a microfluidic chip platform integrated with primary cell‐laden microcapsules. Gradient drug screening reveals individualized treatment response variations among patients and their correlation with clinical outcomes.
Qiong Chen, Jing Wang, Wenzhao Li, Luoran Shang, Dexuan Wang, Ping Duan   +5 more
wiley   +1 more source

Study protocol: NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC trial): a randomised controlled trial [PDF]

, 2019
Introduction Congenital heart disease (CHD) is a major cause of infant mortality. Many infants with CHD require corrective surgery with most operations requiring cardiopulmonary bypass (CPB).
, Alphonso, Nelson, Beca, John, Blumenthal, Antje, Butt, Warwick, d'Udekem, Yves, Delzoppo, Carmel, Erickson, Simon, Festa, Marino, Fooken, Jonas, Gannon, B, Horton, Stephen Brian, Johnson, Kerry, Jones, Mark, Long, Debbie Amanda, Schibler, Andreas, Schlapbach, Luregn J, van Loon, Kim, Winlaw, David, Young, Paul   +19 more
core   +3 more sources

ANESTHETIC PROBLEMS IN CARDIOPULMONARY BYPASS FOR OPEN HEART SURGERY [PDF]

, 1958
Arthur S. Keats, YOSMO KUROSU, Jane Telford, Denton A. Cooley   +3 more
openalex   +1 more source

Precision‐Guided Stealth Missiles in Biomedicine: Biological Carrier‐Mediated Nanomedicine Hitchhiking Strategy

Advanced Science, EarlyView.
Diagram illustrating the binding methods of NPs and biological barriers. The biological carrier‐mediated nanomedicine hitchhiking strategy (BCM‐NHS) utilizes two distinct techniques: the surface‐based “Backpack” method, which relies on ligand‐receptor binding, covalent conjugation, and non‐covalent binding, and the encapsulated “Trojan horse” approach,
Yuyan Zhou, Xinyue Wang, Deyu Zhang, Hanxiao Cui, Xiaorong Tian, Wei Du, Zhenghui Yang, Dongling Wan, Zhiwei Qiu, Chao Liu, Zhicheng Yang, Lizhihong Zhang, Qiusheng Yang, Xuefeng Xu, Wenhao Li, Dong Wang, Haojie Huang, Wencheng Wu   +17 more
wiley   +1 more source

Long‐term outcome prediction for chronic thromboembolic pulmonary hypertension after pulmonary endarterectomy

Clinical Cardiology, Volume 45, Issue 12, Page 1255-1263, December 2022., 2022
Abstract Background The definitive treatment for chronic thromboembolic pulmonary hypertension (CTEPH) is pulmonary endarterectomy (PEA), which has good long‐term outcomes. However, after surgery, a quarter of the patients still have residual pulmonary hypertension (RPH). In pulmonary hemodynamics, there are no unified criteria for RPH, even though the
Wu Song, Jiade Zhu, ZhaoJi Zhong, Yunhu Song, Sheng Liu   +4 more
wiley   +1 more source